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Prions

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Cover of 'Prions'

Table of Contents

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    Book Overview
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    Chapter 1 Purification and Fibrillation of Full-Length Recombinant PrP
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    Chapter 2 Method for Folding of Recombinant Prion Protein to Soluble β-Sheet Secondary Structure
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    Chapter 3 Analysis of Prion Protein Conformation Using Circular Dichroism Spectroscopy
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    Chapter 4 Analysis of Prion Protein Structure Using Nuclear Magnetic Resonance Spectroscopy
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    Chapter 5 Immunodetection of PrP Sc Using Western Immunoblotting Techniques
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    Chapter 6 Analysis of miRNA Signatures in Neurodegenerative Prion Disease
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    Chapter 7 Cell Biology Approaches to Studying Prion Diseases
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    Chapter 8 Expression of Heterologous PrP and Prion Propagation in RK13 Cells
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    Chapter 9 Generation of Infectious Prions and Detection with the Prion-Infected Cell Assay
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    Chapter 10 Analysis of Cellular Prion Protein Endoproteolytic Processing
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    Chapter 11 Cellular Analysis of Adult Neural Stem Cells for Investigating Prion Biology
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    Chapter 12 Neurotoxicity of Prion Peptides on Cultured Cerebellar Neurons
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    Chapter 13 Methods of Protein Misfolding Cyclic Amplification
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    Chapter 14 RT-QuIC Assays for Prion Disease Detection and Diagnostics
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    Chapter 15 A Quick Method to Evaluate the Effect of the Amino Acid Sequence in the Misfolding Proneness of the Prion Protein
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    Chapter 16 Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases
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    Chapter 17 In Vivo-Near Infrared Imaging of Neurodegeneration
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    Chapter 18 Strain Typing of Prion Diseases Using In Vivo Mouse Models
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    Chapter 19 Preparation and Immunostaining of the Myenteric Plexus of Prion-Infected Mice
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    Chapter 20 Cell Culture Methods for Screening of Prion Therapeutics
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    Chapter 21 Real-Time Quaking-Induced Conversion for Diagnosis of Prion Disease
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    Chapter 22 Methods for Molecular Diagnosis of Human Prion Disease
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    Chapter 23 Molecular Subtyping of PrPres in Human Sporadic CJD Brain Tissue
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    Chapter 24 Intercellular Prion-Like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture
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