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Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations

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Cover of 'Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations'

Table of Contents

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    Book Overview
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    Chapter 1 Evolution of Immunity and Pathogens.
  3. Altmetric Badge
    Chapter 2 A Host–Pathogen Interaction Reduced to First Principles: Antigenic Variation in T. brucei
  4. Altmetric Badge
    Chapter 3 Antigenic Variation in Plasmodium falciparum.
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    Chapter 4 Polymorphic Mucin-Like Proteins in Schistosoma mansoni, a Variable Antigen and a Key Component of the Compatibility Between the Schistosome and Its Snail Host.
  6. Altmetric Badge
    Chapter 5 Fibrinogen-Related Proteins (FREPs) in Mollusks.
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    Chapter 6 Somatic and Germline Diversification of a Putative Immunoreceptor within One Phylum: Dscam in Arthropods.
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    Chapter 7 An Immune Effector System in the Protochordate Gut Sheds Light on Fundamental Aspects of Vertebrate Immunity.
  9. Altmetric Badge
    Chapter 8 Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
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    Chapter 9 Antibody Repertoires in Fish.
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    Chapter 10 Unique Features of Fish Immune Repertoires: Particularities of Adaptive Immunity Within the Largest Group of Vertebrates.
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    Chapter 11 The Evolution and Structure of Atypical T Cell Receptors
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    Chapter 12 Diversification of the Primary Antibody Repertoire by AID-Mediated Gene Conversion.
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    Chapter 13 Antibody Isotype Switching in Vertebrates.
Attention for Chapter 9: Antibody Repertoires in Fish.
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Chapter title
Antibody Repertoires in Fish.
Chapter number 9
Book title
Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
Published in
Results and problems in cell differentiation, January 2015
DOI 10.1007/978-3-319-20819-0_9
Pubmed ID
26537383
Book ISBNs
978-3-31-920818-3, 978-3-31-920819-0
Authors

Bengtén, Eva, Wilson, Melanie, Eva Bengtén, Melanie Wilson

Abstract

As in mammals, cartilaginous and teleost fishes possess adaptive immune systems based on antigen recognition by immunoglobulins (Ig), T cell receptors (TCR), and major histocompatibility complex molecules (MHC) I and MHC II molecules. Also it is well established that fish B cells and mammalian B cells share many similarities, including Ig gene rearrangements, and production of membrane Ig and secreted Ig forms. This chapter provides an overview of the IgH and IgL chains in cartilaginous and bony fish, including their gene organizations, expression, diversity of their isotypes, and development of the primary repertoire. Furthermore, when possible, we have included summaries of key studies on immune mechanisms such as allelic exclusion, somatic hypermutation, affinity maturation, class switching, and mucosal immune responses.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 25%
Student > Bachelor 2 8%
Professor 2 8%
Student > Ph. D. Student 2 8%
Student > Postgraduate 2 8%
Other 2 8%
Unknown 8 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 25%
Agricultural and Biological Sciences 4 17%
Immunology and Microbiology 3 13%
Unspecified 1 4%
Medicine and Dentistry 1 4%
Other 0 0%
Unknown 9 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2016.
All research outputs
#18,430,119
of 22,832,057 outputs
Outputs from Results and problems in cell differentiation
#134
of 217 outputs
Outputs of similar age
#255,915
of 353,176 outputs
Outputs of similar age from Results and problems in cell differentiation
#9
of 17 outputs
Altmetric has tracked 22,832,057 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 217 research outputs from this source. They receive a mean Attention Score of 2.1. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.

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