Chapter title |
Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
|
---|---|
Chapter number | 8 |
Book title |
Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
|
Published in |
Results and problems in cell differentiation, January 2015
|
DOI | 10.1007/978-3-319-20819-0_8 |
Pubmed ID | |
Book ISBNs |
978-3-31-920818-3, 978-3-31-920819-0
|
Authors |
Kasahara, Masanori, Masanori Kasahara |
Abstract |
Jawless vertebrates represented by lampreys and hagfish mount antigen-specific immune responses using variable lymphocyte receptors. These receptors generate diversity comparable to that of T-cell and B-cell receptors by assembling multiple leucine-rich repeat modules with highly variable sequences. Although it is true that jawed and jawless vertebrates have structurally unrelated antigen receptors, their adaptive immune systems have much in common. Most notable is the conservation of lymphocyte lineages. It appears that specialized lymphocyte lineages emerged in a common vertebrate ancestor and that jawed and jawless vertebrates co-opted different antigen receptors within the context of such lymphocyte lineages. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 31% |
Student > Master | 3 | 23% |
Student > Bachelor | 1 | 8% |
Researcher | 1 | 8% |
Professor > Associate Professor | 1 | 8% |
Other | 0 | 0% |
Unknown | 3 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 23% |
Medicine and Dentistry | 2 | 15% |
Chemistry | 2 | 15% |
Immunology and Microbiology | 1 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Other | 1 | 8% |
Unknown | 3 | 23% |