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Ligand-Macromolecular Interactions in Drug Discovery

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Cover of 'Ligand-Macromolecular Interactions in Drug Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 An Historical Overview of Drug Discovery
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    Chapter 2 Ligand Macromolecule Interactions: Theoretical Principles of Molecular Recognition
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    Chapter 3 X-ray crystallography in drug discovery.
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    Chapter 4 Virtual Screening of Compound Libraries
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    Chapter 5 Combinatorial Chemistry and the Synthesis of Compound Libraries
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    Chapter 6 Ligand-Based Nuclear Magnetic Resonance Screening Techniques
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    Chapter 7 Isothermal Titration Calorimetry and Differential Scanning Calorimetry
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    Chapter 8 Adaptive Combinatorial Design of Focused Compound Libraries
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    Chapter 9 Chemical Microarrays: A New Tool for Discovery Enzyme Inhibitors
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    Chapter 10 Fluorescence Polarization and Time-Resolved Fluorescence Resonance Energy Transfer Techniques for PI3K Assays
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    Chapter 11 Small Molecule Protein Interaction Profiling with Functional Protein Microarrays
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    Chapter 12 Capillary Electrophoresis in Drug Discovery
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    Chapter 13 SPR in Drug Discovery: Searching Bioactive Compounds in Plant Extracts
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    Chapter 14 Application of Frontal Affinity Chromatography with Mass Spectrometry (FAC–MS) for Stereospecific Ligand–Macromolecule Interaction, Detection and Screening
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    Chapter 15 GPC Spin Column HPLC–ESI-MS Methods for Screening Drugs Noncovalently Bound to Proteins
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    Chapter 16 A scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening.
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    Chapter 17 A Natural Products Approach to Drug Discovery: Probing Modes of Action of Antitumor Agents by Genome-Scale cDNA Library Screening
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    Chapter 18 Ligand–Macromolecule Interactions in Live Cells by Fluorescence Correlation Spectroscopy
Attention for Chapter 5: Combinatorial Chemistry and the Synthesis of Compound Libraries
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Citations

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Chapter title
Combinatorial Chemistry and the Synthesis of Compound Libraries
Chapter number 5
Book title
Ligand-Macromolecular Interactions in Drug Discovery
Published in
Methods in molecular biology, January 2010
DOI 10.1007/978-1-60761-244-5_5
Pubmed ID
Book ISBNs
978-1-60761-243-8, 978-1-60761-244-5
Authors

Rolf Breinbauer, Matthias Mentel

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Uruguay 1 17%
Unknown 5 83%

Demographic breakdown

Readers by professional status Count As %
Lecturer 1 17%
Student > Bachelor 1 17%
Professor 1 17%
Student > Master 1 17%
Professor > Associate Professor 1 17%
Other 0 0%
Unknown 1 17%
Readers by discipline Count As %
Chemistry 2 33%
Pharmacology, Toxicology and Pharmaceutical Science 1 17%
Medicine and Dentistry 1 17%
Unknown 2 33%