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Hedgehog Signaling Protocols

Overview of attention for book
Cover of 'Hedgehog Signaling Protocols'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Controlled Delivery of Sonic Hedgehog with a Heparin-Based Coacervate
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    Chapter 2 In Vivo Imaging of Hedgehog Transport in Drosophila Epithelia.
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    Chapter 3 Modeling Hedgehog Signaling Through Flux-Saturated Mechanisms
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    Chapter 4 Evaluating the Activity of Smoothened Toward G Proteins Using [ 35 S]Guanosine 5′-(3- O -thio)triphosphate ([ 35 S]GTPγS)
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    Chapter 5 Analysis of Smoothened Phosphorylation and Activation in Cultured Cells and Wing Discs of Drosophila
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    Chapter 6 Hedgehog Signaling Protocols
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    Chapter 7 Luciferase Reporter Assays to Study Transcriptional Activity of Hedgehog Signaling in Normal and Cancer Cells
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    Chapter 8 Measuring Expression Levels of Endogenous Gli Genes by Immunoblotting and Real-Time PCR
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    Chapter 9 Quantitative Immunoblotting of Endogenous Hedgehog Pathway Components
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    Chapter 10 Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry
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    Chapter 11 Rapid Screening of Gli2/3 Mutants Using the Flp-In System
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    Chapter 12 Insights into Gli Factors Ubiquitylation Methods
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    Chapter 13 Determination of Acetylation of the Gli Transcription Factors
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    Chapter 14 Efficient Detection of Indian Hedgehog During Endochondral Ossification by Whole-Mount Immunofluorescence
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    Chapter 15 Methods for Detection of Ptc1-Driven LacZ Expression in Adult Mouse Skin
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    Chapter 16 Determination and Analysis of Cellular Metabolic Changes by Noncanonical Hedgehog Signaling.
Attention for Chapter 16: Determination and Analysis of Cellular Metabolic Changes by Noncanonical Hedgehog Signaling.
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Chapter title
Determination and Analysis of Cellular Metabolic Changes by Noncanonical Hedgehog Signaling.
Chapter number 16
Book title
Hedgehog Signaling Protocols
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-2772-2_16
Pubmed ID
Book ISBNs
978-1-4939-2771-5, 978-1-4939-2772-2
Authors

Teperino, Raffaele, Pospisilik, John Andrew, Raffaele Teperino, John Andrew Pospisilik

Abstract

Hedgehog is a morphogen essential for body patterning and proper embryonic development from flies to humans. Thought quiescent in adults, its inappropriate reactivation is associated with many disparate genetic and sporadic types of human cancers. Recent findings have demonstrated a key, yet unexpected, role of the Hedgehog signaling pathway in metabolic control. Here, we describe a panel of methods to determine and analyze cellular and organismal metabolic changes downstream of the Hedgehog signaling pathway.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 33%
Professor > Associate Professor 1 17%
Student > Postgraduate 1 17%
Student > Doctoral Student 1 17%
Unknown 1 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 50%
Neuroscience 1 17%
Medicine and Dentistry 1 17%
Unknown 1 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2015.
All research outputs
#15,340,005
of 22,817,213 outputs
Outputs from Methods in molecular biology
#5,340
of 13,121 outputs
Outputs of similar age
#208,992
of 353,112 outputs
Outputs of similar age from Methods in molecular biology
#346
of 997 outputs
Altmetric has tracked 22,817,213 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,121 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,112 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 997 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.