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Biochirality

Overview of attention for book
Attention for Chapter 367: Synthesis and Chirality of Amino Acids Under Interstellar Conditions.
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10 Mendeley
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Chapter title
Synthesis and Chirality of Amino Acids Under Interstellar Conditions.
Chapter number 367
Book title
Biochirality
Published in
Topics in current chemistry, September 2012
DOI 10.1007/128_2012_367
Pubmed ID
Book ISBNs
978-3-64-237625-2, 978-3-64-237626-9
Authors

Giri C, Goesmann F, Meinert C, Evans AC, Meierhenrich UJ, Chaitanya Giri, Fred Goesmann, Cornelia Meinert, Amanda C. Evans, Uwe J. Meierhenrich

Abstract

Amino acids are the fundamental building blocks of proteins, the biomolecules that provide cellular structure and function in all living organisms. A majority of amino acids utilized within living systems possess pre-specified orientation geometry (chirality); however the original source for this specific orientation remains uncertain. In order to trace the chemical evolution of life, an appreciation of the synthetic and evolutional origins of the first chiral amino acids must first be gained. Given that the amino acids in our universe are likely to have been synthesized in molecular clouds in interstellar space, it is necessary to understand where and how the first synthesis might have occurred. The asymmetry of the original amino acid synthesis was probably the result of exposure to chiral photons in the form of circularly polarized light (CPL), which has been detected in interstellar molecular clouds. This chirality transfer event, from photons to amino acids, has been successfully recreated experimentally and is likely a combination of both asymmetric synthesis and enantioselective photolysis. A series of innovative studies have reported successful simulation of these environments and afforded production of chiral amino acids under realistic circumstellar and interstellar conditions: irradiation of interstellar ice analogues (CO, CO2, NH3, CH3OH, and H2O) with circularly polarized ultraviolet photons at low temperatures does result in enantiomer enriched amino acid structures (up to 1.3% ee). This topical review summarizes current knowledge and recent discoveries about the simulated interstellar environments within which amino acids were probably formed. A synopsis of the COSAC experiment onboard the ESA cometary mission ROSETTA concludes this review: the ROSETTA mission will soft-land on the nucleus of the comet 67P/Churyumov-Gerasimenko in November 2014, anticipating the first in situ detection of asymmetric organic molecules in cometary ices.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Belgium 1 10%
Unknown 9 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 50%
Researcher 3 30%
Student > Doctoral Student 1 10%
Unknown 1 10%
Readers by discipline Count As %
Chemistry 6 60%
Agricultural and Biological Sciences 1 10%
Materials Science 1 10%
Pharmacology, Toxicology and Pharmaceutical Science 1 10%
Unknown 1 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2016.
All research outputs
#4,722,851
of 8,745,601 outputs
Outputs from Topics in current chemistry
#59
of 116 outputs
Outputs of similar age
#97,640
of 196,706 outputs
Outputs of similar age from Topics in current chemistry
#1
of 2 outputs
Altmetric has tracked 8,745,601 research outputs across all sources so far. This one is in the 27th percentile – i.e., 27% of other outputs scored the same or lower than it.
So far Altmetric has tracked 116 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,706 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them