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Current Trends in Monoclonal Antibody Development and Manufacturing

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Cover of 'Current Trends in Monoclonal Antibody Development and Manufacturing'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction
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    Chapter 2 CDR Repair: A Novel Approach to Antibody Humanization
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    Chapter 3 Nanobodies, Single-Domain Antigen-Binding Fragments of Camelid Heavy-Chain Antibodies
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    Chapter 4 GPEx ® A Flexible Method for the Rapid Generation of Stable, High Expressing, Antibody Producing Mammalian Cell Lines
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    Chapter 5 Advancing Our Cell Culture Platform: Incorporating Lessons Learned and New Technologies
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    Chapter 6 Addressing Changes Associated with Technology Transfer: A Case Study
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    Chapter 7 Concepts for Disposables in Biopharmaceutical Manufacture
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    Chapter 8 Formulation and Delivery Issues for Monoclonal Antibody Therapeutics
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    Chapter 9 Challenges in the Development of High Protein Concentration Formulations
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    Chapter 10 Protein Immobilization by Crystallization and Precipitation: An Alternative to Lyophilization
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    Chapter 11 Characterizing High Affinity Antigen/Antibody Complexes by Kinetic and Equilibrium Based Methods
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    Chapter 12 Analytical Characterization of Monoclonal Antibodies: Linking Structure to Function
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    Chapter 13 Analysis of Irreversible Aggregation, Reversible Self-association and Fragmentation of Monoclonal Antibodies by Analytical Ultracentrifugation
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    Chapter 14 Biophysical Signatures of Monoclonal Antibodies
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    Chapter 15 Impact of Fc Glycosylation on Monoclonal Antibody Effector Functions and Degradation by Proteases
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    Chapter 16 Immunogenicity Assessment of Antibody Therapeutics
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    Chapter 17 Production of Monoclonal Antibodies in E. coli
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    Chapter 18 Recent Advancements in the Use of Antibody Drug Conjugates for Cancer Therapy
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    Chapter 19 Antibody Radiolabeling
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Current Trends in Monoclonal Antibody Development and Manufacturing
Published by
Springer New York, November 2009
DOI 10.1007/978-0-387-76643-0
978-0-387-76642-3, 978-0-387-76643-0

Shire, Steven J., Gombotz, Wayne, Bechtold-Peters, Karoline, Andya, James

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 4%
Italy 1 <1%
France 1 <1%
Mexico 1 <1%
China 1 <1%
Colombia 1 <1%
Unknown 125 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 38 28%
Student > Ph. D. Student 26 19%
Student > Master 17 13%
Student > Bachelor 16 12%
Other 12 9%
Other 14 10%
Unknown 12 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 46 34%
Biochemistry, Genetics and Molecular Biology 17 13%
Engineering 15 11%
Chemistry 13 10%
Pharmacology, Toxicology and Pharmaceutical Science 10 7%
Other 21 16%
Unknown 13 10%