| Chapter title |
Natural Products from Photorhabdus and Other Entomopathogenic Bacteria
|
|---|---|
| Chapter number | 24 |
| Book title |
The Molecular Biology of Photorhabdus Bacteria
|
| Published in |
Current topics in microbiology and immunology, January 2016
|
| DOI | 10.1007/82_2016_24 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-952714-7, 978-3-31-952715-4
|
| Authors |
Kenan A. J. Bozhüyük, Qiuqin Zhou, Yvonne Engel, Antje Heinrich, Alexander Pérez, Helge B. Bode |
| Abstract |
Although the first natural products (NP) from Photorhabdus and Xenorhabdus bacteria have been known now for almost 30 years, a huge variety of new compounds have been identified in the last 5-10 years, mainly due to the application of modern mass spectrometry. Additionally, application of molecular methods that allow the activation of NP production in several different strains as well as efficient heterologous expression methods have led to the production and validation of many new compounds. In this chapter we discuss the benefit of using Photorhabdus as a model system for microbial chemical ecology. We also examine non-ribosomal peptide synthetases as the most important pathway for NP production. Finally, we discuss the origin and function of all currently known NPs and the development of the molecular and chemical tools used to identify these NPs faster. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 2 | 13% |
| Researcher | 2 | 13% |
| Student > Ph. D. Student | 2 | 13% |
| Lecturer | 1 | 6% |
| Student > Doctoral Student | 1 | 6% |
| Other | 4 | 25% |
| Unknown | 4 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 44% |
| Biochemistry, Genetics and Molecular Biology | 2 | 13% |
| Environmental Science | 1 | 6% |
| Chemistry | 1 | 6% |
| Engineering | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 4 | 25% |