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Overview of attention for article published in Genome Biology (Online Edition), January 2000
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

news
1 news outlet
patent
2 patents
wikipedia
1 Wikipedia page

Citations

dimensions_citation
578 Dimensions

Readers on

mendeley
440 Mendeley
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Title
Published in
Genome Biology (Online Edition), January 2000
DOI 10.1186/gb-2000-1-6-reviews3003
Pubmed ID
Authors

Danièle Werck-Reichhart, René Feyereisen

Abstract

Cytochrome P450 proteins, named for the absorption band at 450 nm of their carbon-monoxide-bound form, are one of the largest superfamilies of enzyme proteins. The P450 genes (also called CYP) are found in the genomes of virtually all organisms, but their number has exploded in plants. Their amino-acid sequences are extremely diverse, with levels of identity as low as 16% in some cases, but their structural fold has remained the same throughout evolution. P450s are heme-thiolate proteins; their most conserved structural features are related to heme binding and common catalytic properties, the major feature being a completely conserved cysteine serving as fifth (axial) ligand to the heme iron. Canonical P450s use electrons from NAD(P)H to catalyze activation of molecular oxygen, leading to regiospecific and stereospecific oxidative attack of a plethora of substrates. The reactions carried out by P450s, though often hydroxylation, can be extremely diverse and sometimes surprising. They contribute to vital processes such as carbon source assimilation, biosynthesis of hormones and of structural components of living organisms, and also carcinogenesis and degradation of xenobiotics. In plants, chemical defense seems to be a major reason for P450 diversification. In prokaryotes, P450s are soluble proteins. In eukaryotes, they are usually bound to the endoplasmic reticulum or inner mitochondrial membranes. The electron carrier proteins used for conveying reducing equivalents from NAD(P)H differ with subcellular localization. P450 enzymes catalyze many reactions that are important in drug metabolism or that have practical applications in industry; their economic impact is therefore considerable.

Mendeley readers

The data shown below were compiled from readership statistics for 440 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 4 <1%
Mexico 3 <1%
United Kingdom 2 <1%
Canada 1 <1%
Brazil 1 <1%
South Africa 1 <1%
Switzerland 1 <1%
Austria 1 <1%
Germany 1 <1%
Other 6 1%
Unknown 419 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 82 19%
Student > Master 57 13%
Researcher 46 10%
Student > Bachelor 44 10%
Student > Doctoral Student 25 6%
Other 55 13%
Unknown 131 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 141 32%
Biochemistry, Genetics and Molecular Biology 66 15%
Chemistry 31 7%
Pharmacology, Toxicology and Pharmaceutical Science 16 4%
Environmental Science 10 2%
Other 33 8%
Unknown 143 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2020.
All research outputs
#1,586,358
of 16,562,219 outputs
Outputs from Genome Biology (Online Edition)
#1,504
of 3,490 outputs
Outputs of similar age
#30,150
of 295,167 outputs
Outputs of similar age from Genome Biology (Online Edition)
#4
of 6 outputs
Altmetric has tracked 16,562,219 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,490 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,167 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.