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Purine Metabolism in Man—II

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Cover of 'Purine Metabolism in Man—II'

Table of Contents

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    Book Overview
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    Chapter 1 History of Gout
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    Chapter 2 A Multienzyme Complex for De Novo Purine Biosynthesis
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    Chapter 3 Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
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    Chapter 4 Purine toxicity in human lymphoblasts.
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    Chapter 5 Studies on the Regulation of the Biosynthesis of Myocardial Adenine Nucleotides
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    Chapter 6 Effect of Triiodothyronine on the Biosynthesis of Adenine Nucleotides and Proteins in the Rat Heart
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    Chapter 7 Altered Synthesis and Catabolism of Purine Nucleotides in Regulatory Mutants of Saccharomyces Cerevisiae
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    Chapter 8 Phosphoribosylpyrophosphate Synthesis in Human Erythrocytes: Inhibition by Purine Nucleosides
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    Chapter 9 Human Phosphoribosylpyrophosphate Synthetase: Relation of Activity and Quaternary Structure
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    Chapter 10 Transfer of Resistance to Selective Conditions from Fibroblasts with Mutant Feedback-Resistant Phosphoribosylpyrophosphate Synthetase to Normal Cells
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    Chapter 11 Phosphoribosylpyrophosphate Degradation in Human Tissues
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    Chapter 12 Properties of the Phosphoribosylpyrophosphate-Glutamine Amidotransferase of the Human Leucemic Cells
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    Chapter 13 A Purine Auxotroph Deficient in Phosphoribosylpyrophosphate Amidotransferase and Phosphoribosylpyrophosphate Aminotransferase Activities with Normal Activity of Ribose-5-phosphate Aminotransferase
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    Chapter 14 Biochemical Studies of Purine Auxotrophs of Drosophila Melanogaster
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    Chapter 15 Inosine Triphosphate Metabolism in Human Erythrocytes
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    Chapter 16 Oxypurine and 6-Thiopurine Nucleoside Triphosphate Formation in Human Erythrocytes
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    Chapter 17 Activity of the Salvage-Pathway in Erythrocytes of Newborn Infants, Children and Adults
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    Chapter 18 Purine Phosphoribosyl Transferases in Human Erythrocyte Ghosts
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    Chapter 19 The Localisation of the Purine-Phosphoribosyltransferase in Rat Liver Organells
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    Chapter 20 Reversible and Irreversible Inhibition of Hypo-Xanthine-Phosphoribosyltransferase
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    Chapter 21 Purification and characterization of hypoxanthine-guanine phosphoribosyl transferase from cultured HTC cells.
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    Chapter 22 Evidence for the Existence of Different Types of Metabolic Cooperation
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    Chapter 23 Stability of the azaguanine resistant phenotype in vivo.
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    Chapter 24 Functioning of Purine Salvage Pathways in Escherichia Coli K-12
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    Chapter 25 Metabolism of Intravenous Adenine in the Pig
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    Chapter 26 Pattern of Purine-Nucleotide Metabolism in Hepatopancreas of Helix Pomatia (Gastropoda)
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    Chapter 27 Isozymes of AMP Deaminase
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    Chapter 28 Purification of Human Erythrocyte Adenosine Deaminase
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    Chapter 29 Adenosine Deaminase: Characterization of the Molecular Heterogeneity of the Enzyme in Human Tissue
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    Chapter 30 Human 5′-Nucleotidase: Multiple Molecular Forms and Regulation
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    Chapter 31 Subcellular distribution of purine degrading enzymes in the liver of the carp (Cyprinus carpio l.)
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    Chapter 32 Purine Enzyme Abnormalities: A Four Year Experience
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    Chapter 33 Fibroblast Phosphoribosylpyrophosphate and Ribose-5-Phosphate Concentration and Generation in Gout with Purine Overproduction
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    Chapter 34 Familial Distribution of Increased Erythrocyte PP-Ribose-P Levels
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    Chapter 35 X-Linked Pattern of Inheritance of Gout Due to Mutant Feedback-Resistant Phosphoribosylpyrophosphate Synthetase
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    Chapter 36 Incidence of APRT Deficiency
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    Chapter 37 Complete Deficiency of Adenine Phosphoribosyltransferase: Report of a Family
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    Chapter 38 Purine synthesis and excretion in mutants of the WI-L2 human lymphoblastoid line deficient in adenosine kinase (AK) and adenine phosphoribosyltransferase (APRT).
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    Chapter 39 Partial HPRT Deficiency : Heterozygotes Exhibit One Cell Population in Intact Cell Assays
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    Chapter 40 Diminished Affinity for Purine Substrates as a Basis for Gout with Mild Deficiency of Hypoxanthine-Guanine Phosphoribosyltransferase
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    Chapter 41 Purine and Pyrimidine Nucleotide Concentrations in Cells with Decreased Hypoxanthine-Guanine-Phosphoribosyltransferase (HGPRT) Activity
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    Chapter 42 Electrophoretic Variation in Partial Deficiencies of Hypoxanthine-Guanine Phosphoribosyltransferase
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    Chapter 43 Xanthine Oxidase Activity in a Gouty Patient with Partial Deficiency of HGPRT
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    Chapter 44 Experience with Detection of Heterozygous Carriers and Prenatal Diagnosis of Lesch-Nyhan Disease
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    Chapter 45 HGPRT-Positive and HGPRT-Negative Erythrocytes in Heterozygotes for HGPRT Deficiency
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    Chapter 46 Study of Immunoreactive Material in Patients with Deficient HPRT Activity
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    Chapter 47 Effects of Inosine on Purine Synthesis in Normal and HGPRT-Deficient Human Fibroblasts
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    Chapter 48 An Alternate Metabolic Route for the Synthesis of Inosine 5′-Phosphate (IMP) in the Lesch-Nyhan Erythrocyte
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    Chapter 49 Adenosine Metabolism in Permanent Lymphocyte Lines and in Erythrocytes of Patients with the Lesch-Nyhan Syndrome
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    Chapter 50 Purine-Nucleoside Phosphorylase and Adenosine Aminohydrolase Activities in Fibroblasts with the Leschnyhan Mutation
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    Chapter 51 Altered Excretion of 5-Hydroxyindoleacetic Acid and Glycine in Patients with the Lesch-Nyhan Disease
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    Chapter 52 Xanthinuria, Lithiasis and Gout in the Same Family
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    Chapter 53 Immunological Aspects of Purine Metabolism
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    Chapter 54 Phosphoribosylpyrophosphate (PRPP) Amidotransferase (EC 2.4.2.14) Activity in Unstimulated and Stimulated Human Lymphocytes
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    Chapter 55 Adenosine and guanosine metabolism during phytohemagglutinin induced transformation of human lymphocytes.
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    Chapter 56 Adenine and Adenosine Metabolism in Phytohemagglutinin (PHA) — Stimulated and Unstimulated Normal Human Lymphocytes
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    Chapter 57 Adenine and Adenosine Metabolism in Lymphocytes Deficient in Adenosine Deaminase (ADA) Activity
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    Chapter 58 Immunoreactive adenosine deaminase (ADA) in cultured fibroblasts from patients with combined immunodeficiency disease.
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    Chapter 59 Urinary Purines in a Patient with a Severely Defective T Cell Immunity and a Purine Nucleoside Phosphorylase Deficiency
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    Chapter 60 A Second Case of Inosine Phosphorylase Deficiency with Severe T-Cell Abnormalities
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    Chapter 61 Regulation of De Novo Purine Synthesis in Human and Rat Tissue: Role of Oxidative Pentose Phosphate Pathway Activity and of Ribose-5-Phosphate and Phosphoribosylpyrophosphate Availability
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    Chapter 62 Hepatic Gluconeogenesis and Urate Formation from Various Nucleosides
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    Chapter 63 Influence of Carbohydrates on Uric Acid Synthesis in the Isolated Perfused Chicken Liver
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    Chapter 64 Studies on the Influence of Ethanol and of Lactic Acid on Uric Acid Metabolism
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    Chapter 65 Carbohydrate Induced Increase in Uric Acid Synthesis. Studies in Human Volunteers and in Laboratory Rats
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    Chapter 66 Pharmacologically Induced Erythrocyte PP-Ribose-P Variations
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    Chapter 67 Isolated Rat Liver Cells — Purine Metabolism and Effects of Fructose
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    Chapter 68 Studies on the Effect of Fructose and Xylitol in the Rat Liver: 5′-Nucleotidase, Adenosine Deaminase, De Novo Purine Synthesis
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    Chapter 69 The NADP/NADPH 2 Ratio in Erythrocytes of Hyperuricemic Patients, A Possible Regulator Between Purine, Carbohydrate and Lipid Metabolism
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    Chapter 70 Hypertriglyceridaemia and Chenodeoxycholic Acid
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    Chapter 71 Fatty Acid Composition of Plasma Lipid Fractions in Gout
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    Chapter 72 An Improved Method for the Electrophoretic Separation and Histochemical Identification of 5-Phosphoribosyl-1-Pyrophosphate Synthetase Using Microgram Quantities of Crude Cell Extracts
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    Chapter 73 A New Assay for the Determination of Phosphoribosylamine
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    Chapter 74 Facilitated Purification of Hypoxanthine-Phosphoribosyltransferase by Affinity Chromatography
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    Chapter 75 Ultramicrochemistry: A Contribution to the Analysis of Purine Metabolism in Man
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    Chapter 76 Ultramicrochemical Studies on Enzyme Kinetics
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    Chapter 77 Localization of Xanthine Oxidase Activity in Hepatic Tissue
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    Chapter 78 Analysis of Purines and their Nucleosides by the Reverse Phase Partition Mode of High Pressure Liquid Chromatography
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    Chapter 79 Enzymatic Determination of Urate, Cholesterol and Triglycerides in the Synovial Fluid with the Centrifugal Fast Analyzer
Attention for Chapter 42: Electrophoretic Variation in Partial Deficiencies of Hypoxanthine-Guanine Phosphoribosyltransferase
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Chapter title
Electrophoretic Variation in Partial Deficiencies of Hypoxanthine-Guanine Phosphoribosyltransferase
Chapter number 42
Book title
Purine Metabolism in Man—II
Published by
Springer, Boston, MA, January 1977
DOI 10.1007/978-1-4613-4223-6_42
Pubmed ID
Book ISBNs
978-1-4613-4225-0, 978-1-4613-4223-6
Authors

Irving H. Fox, Sheila Lacroix, Fox, Irving H., Lacroix, Sheila