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MicroRNA and Cancer

Overview of attention for book
Cover of 'MicroRNA and Cancer'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Noncoding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics
  3. Altmetric Badge
    Chapter 2 MicroRNAs in Breast Cancer: Diagnostic and Therapeutic Potential
  4. Altmetric Badge
    Chapter 3 Involvement of miRNAs and Pseudogenes in Cancer
  5. Altmetric Badge
    Chapter 4 MicroRNAs Reprogram Tumor Immune Response
  6. Altmetric Badge
    Chapter 5 Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like Gene Expression, RNA Editing, and MicroRNAs Regulation
  7. Altmetric Badge
    Chapter 6 MicroRNAs Change the Landscape of Cancer Resistance
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    Chapter 7 MicroRNA, Noise, and Gene Expression Regulation
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    Chapter 8 Deep Sequencing Reveals a MicroRNA Expression Signature in Triple-Negative Breast Cancer
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    Chapter 9 Detection of Plasma MicroRNA Signature in Osteosarcoma Patients
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    Chapter 10 Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells
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    Chapter 11 Combination of Anti-miRNAs Oligonucleotides with Low Amounts of Chemotherapeutic Agents for Pancreatic Cancer Therapy
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    Chapter 12 Evaluation of MicroRNA Delivery In Vivo
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    Chapter 13 Angiogenesis Analysis by In Vitro Coculture Assays in Transwell Chambers in Ovarian Cancer
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    Chapter 14 Application of Individual qPCR Performance Parameters for Quality Control of Circulating MicroRNA Data
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    Chapter 15 Construction of Multi-Potent MicroRNA Sponge and Its Functional Evaluation
  17. Altmetric Badge
    Chapter 16 MicroRNA Sequencing Data Analysis Toolkits
Attention for Chapter 5: Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like Gene Expression, RNA Editing, and MicroRNAs Regulation
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#17 of 9,631)
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

news
7 news outlets
twitter
1 tweeter

Citations

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1 Dimensions

Readers on

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9 Mendeley
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Chapter title
Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like Gene Expression, RNA Editing, and MicroRNAs Regulation
Chapter number 5
Book title
MicroRNA and Cancer
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7435-1_5
Pubmed ID
Book ISBNs
978-1-4939-7433-7, 978-1-4939-7435-1
Authors

Wei Cao, Wei Wu, Cao, Wei, Wu, Wei

Abstract

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) protein family is encoded by eleven genes located in human genome. APOBECs are a family of evolutionarily conserved cytidine deaminases in vertebrates, and particularly in mammals. APOBECs play key roles in innate immunity against viral infection and retrotransposons. Subtypes of APOBEC3 can cause specific mutations in RNA and DNA at distinct preferred nucleotide contexts in human cancer. The pervasive APOBEC3s activation in the host genome converts cytosine to uracile on single-stranded DNA, which has been suggested to depend on ATR/chk1 pathways. In this chapter, we review the expression profiling of APOBEC expression in normal and disease states, discuss how microRNAs interact with APOBEC gene family, and post-transcriptionally regulate APOBEC gene expression in the APOBECA-B fusion allele and APOBEC-mediated RNA editing. It is reasonable to speculate targeting specific microRNAs may reduce host genome mutagenesis via inactivation of APOBEC deaminases.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 33%
Student > Master 3 33%
Researcher 1 11%
Student > Bachelor 1 11%
Unknown 1 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 56%
Arts and Humanities 1 11%
Unknown 3 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2020.
All research outputs
#408,018
of 16,649,395 outputs
Outputs from Methods in molecular biology
#17
of 9,631 outputs
Outputs of similar age
#14,247
of 326,067 outputs
Outputs of similar age from Methods in molecular biology
#1
of 1 outputs
Altmetric has tracked 16,649,395 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,631 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,067 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them