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Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays

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Cover of 'Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays'

Table of Contents

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    Book Overview
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    Chapter 1 Status of Safety Pharmacology and Present Guidelines
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    Chapter 2 Safety Pharmacology: Introduction
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    Chapter 3 Central Nervous System (CNS) Safety Pharmacology Studies
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    Chapter 4 Methods in Cardiovascular Safety Pharmacology
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    Chapter 5 Renal System in Safety Pharmacology
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    Chapter 6 Respiratory Function Assays in Safety Pharmacology
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    Chapter 7 Safety Pharmacology in Metabolism Pharmacology
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    Chapter 8 Peripheral Nervous System
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    Chapter 9 Safety of Intravenous and Inhalation Anesthetics
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    Chapter 10 Drug-Addiction and Drug-Dependency
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    Chapter 12 Blood Constituents and Safety Pharmacology
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    Chapter 14 Ocular Safety Tests
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    Chapter 15 Side Effects of Central Analgesic Drugs
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    Chapter 16 Endocrine Pharmacology
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    Chapter 17 Skin Pharmacology
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    Chapter 18 Safety Pharmacology Assessment of Biopharmaceuticals
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    Chapter 19 Magnetic Resonance Imaging in Pharmaceutical Safety Assessment
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    Chapter 20 Oncology Pharmacology
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    Chapter 21 Transgenic Animals
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    Chapter 22 Zebrafish in Drug Discovery: Safety Assessment
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    Chapter 23 Chronobiology and the Implications for Safety Pharmacology
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    Chapter 25 Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic Acids, and Mammalian Cells
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    Chapter 27 Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
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    Chapter 28 Safe Chemicals/REACH
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    Chapter 29 Study Design and Statistics
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    Chapter 30 Safety Pharmacokinetics: Introduction
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    Chapter 31 Absorption: In Vitro Tests – Cell Based
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    Chapter 32 Absorption: In Vitro Tests – Non Cell Based
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    Chapter 33 Absorption: In Vivo Tests (Radiolabeled)
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    Chapter 34 Bioanalytical Assays: Gas Chromatography (GC)
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    Chapter 35 Bioanalytical Assays LC-MS/MS
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    Chapter 36 Bioanalytical Assays: RIA/EIA
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    Chapter 37 Bioanalytical Assays – Toxicokinetics
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    Chapter 38 Distribution: Across Barriers
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    Chapter 39 Distribution - In Vitro Tests - Protein Binding
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    Chapter 40 Distribution – In Vivo – Perfused Organs
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    Chapter 41 Distribution In Vivo: Other Methods
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    Chapter 42 Distribution In Vivo
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    Chapter 43 Drug–Drug Interaction: Enzyme Induction
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    Chapter 44 Drug–Drug Interaction: Enzyme Inhibition
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    Chapter 45 In-Silico ADME Modeling
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    Chapter 46 Metabolism Studies In Vitro and In Vivo
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    Chapter 47 Pharmacogenomics in Drug Metabolizing Enzymes and Transporters
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    Chapter 48 Physicochemical Properties
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    Chapter 49 Clinical Pharmacokinetic Studies
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    Chapter 50 Population Pharmacokinetics
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    Chapter 51 Typical PK/PD Approaches in Preclinical and Clinical Development
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    Chapter 52 Safety Toxicology: Introduction
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    Chapter 53 International Guidelines
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    Chapter 54 Testing of Medical Devices
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    Chapter 55 In Silico Methods
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    Chapter 57 Genotoxicity
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    Chapter 58 Reproductive Toxicology
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    Chapter 60 In Vitro Toxicology
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    Chapter 61 OMICS Technologies
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Title
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
Published by
Springer Berlin Heidelberg, March 2013
DOI 10.1007/978-3-642-25240-2
ISBNs
978-3-64-225239-6, 978-3-64-225240-2
Editors

Vogel, H. Gerhard, Maas, Jochen, Hock, Franz J., Mayer, Dieter

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
United Kingdom 2 1%
Denmark 1 <1%
Spain 1 <1%
Netherlands 1 <1%
Unknown 136 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 32 22%
Student > Ph. D. Student 25 17%
Student > Bachelor 23 16%
Researcher 21 15%
Student > Doctoral Student 8 6%
Other 20 14%
Unknown 14 10%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 35 24%
Agricultural and Biological Sciences 20 14%
Chemistry 18 13%
Medicine and Dentistry 15 10%
Biochemistry, Genetics and Molecular Biology 11 8%
Other 27 19%
Unknown 17 12%