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Influenza and Respiratory Care

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Attention for Chapter 181: Rapid Influenza Diagnostic Tests Improve Suitability of Antiviral Treatment in Hospitalized Children
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Chapter title
Rapid Influenza Diagnostic Tests Improve Suitability of Antiviral Treatment in Hospitalized Children
Chapter number 181
Book title
Influenza and Respiratory Care
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/5584_2016_181
Pubmed ID
Book ISBNs
978-3-31-951711-7, 978-3-31-951712-4
Authors

Aneta Nitsch-Osuch, Ernest Kuchar, Izabela Gołębiak, Krzysztof Kanecki, Patryk Tarka, Lidia B. Brydak, Nitsch-Osuch, Aneta, Kuchar, Ernest, Gołębiak, Izabela, Kanecki, Krzysztof, Tarka, Patryk, Brydak, Lidia B.

Abstract

Influenza may have a complicated course in young children. The aim of the study was to analyze the suitability of influenza treatment among children younger than 5 years hospitalized due to an influenza-like illness. We conducted a comparison of the treatment among children hospitalized in two consecutive years: 2015, when no rapid influenza diagnostic tests (RIDT) were in use, and 2016, when RIDT were implemented into a routine practice in the pediatric ward. In both seasons, nasopharyngeal swabs were collected and examined with real time qRT-PCR. In the 2015 season, influenza was diagnosed in 15/52 (28 %) children and none of them received oseltamivir, while 14/15 (93 %) patients received antibiotics. In the 2016 season, influenza was diagnosed in 11/63 (17 %) children, 7/11 (64 %) of them received oseltamivir and another 7/11 (64 %) received antibiotics. In four cases antibiotics overlapped oseltamivir. These differences in the use of oseltamivir and antibiotics were statistically significant (p < 0.05). We conclude that the implementation of RIDT improves the suitability of influenza treatment and decreases the frequency of antibiotic therapy. RIDT should be available in pediatric departments to optimize influenza treatment.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 18%
Researcher 2 18%
Lecturer > Senior Lecturer 1 9%
Professor 1 9%
Other 1 9%
Other 2 18%
Unknown 2 18%
Readers by discipline Count As %
Medicine and Dentistry 5 45%
Nursing and Health Professions 1 9%
Biochemistry, Genetics and Molecular Biology 1 9%
Unknown 4 36%