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Stem Cells and Good Manufacturing Practices

Overview of attention for book
Cover of 'Stem Cells and Good Manufacturing Practices'

Table of Contents

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    Book Overview
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    Chapter 100 Scalable Ex Vivo Expansion of Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Stirred Culture Systems
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    Chapter 101 GMP-Grade Human Fetal Liver-Derived Mesenchymal Stem Cells for Clinical Transplantation
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    Chapter 102 Culture of Human Limbal Epithelial Stem Cells on Tenon’s Fibroblast Feeder-Layers: A Translational Approach
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    Chapter 103 Standard Operating Procedure for the Good Manufacturing Practice-Compliant Production of Human Bone Marrow Mesenchymal Stem Cells
  6. Altmetric Badge
    Chapter 104 Media Fill for Validation of a Good Manufacturing Practice-Compliant Cell Production Process
  7. Altmetric Badge
    Chapter 105 cGMP-Compliant Transportation Conditions for a Prompt Therapeutic Use of Marrow Mesenchymal Stromal/Stem Cells
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    Chapter 106 Scalable Expansion of Human-Induced Pluripotent Stem Cells in Xeno-Free Microcarriers
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    Chapter 112 GMP-Compliant Human Adipose Tissue-Derived Mesenchymal Stem Cells for Cellular Therapy
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    Chapter 115 Purification of Human Induced Pluripotent Stem Cell-Derived Neural Precursors Using Magnetic Activated Cell Sorting
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    Chapter 116 Isolation and Expansion of Mesenchymal Stromal/Stem Cells from Umbilical Cord Under Chemically Defined Conditions
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    Chapter 117 Bioreactor Expansion of Human Mesenchymal Stem Cells According to GMP Requirements
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    Chapter 118 The Suspension Culture of Undifferentiated Human Pluripotent Stem Cells Using Spinner Flasks
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    Chapter 122 Xeno-Free Culture of Human Periodontal Ligament Stem Cells.
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    Chapter 123 Labeling Pluripotent Stem Cell-Derived Neural Progenitors with Iron Oxide Particles for Magnetic Resonance Imaging.
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    Chapter 124 Derivation of GMP-Compliant Integration-Free hiPSCs Using Modified mRNAs
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    Chapter 125 Production of Good Manufacturing Practice-Grade Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells for Therapeutic Use
  18. Altmetric Badge
    Chapter 164 Using the Quantum Cell Expansion System for the Automated Expansion of Clinical-Grade Bone Marrow-Derived Human Mesenchymal Stromal Cells
  19. Altmetric Badge
    Chapter 175 Therapeutic Mesenchymal Stromal Cells: Where We Are Headed
Attention for Chapter 116: Isolation and Expansion of Mesenchymal Stromal/Stem Cells from Umbilical Cord Under Chemically Defined Conditions
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  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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Chapter title
Isolation and Expansion of Mesenchymal Stromal/Stem Cells from Umbilical Cord Under Chemically Defined Conditions
Chapter number 116
Book title
Stem Cells and Good Manufacturing Practices
Published in
Methods in molecular biology, August 2014
DOI 10.1007/7651_2014_116
Pubmed ID
Book ISBNs
978-1-4939-2434-9, 978-1-4939-2435-6
Authors

Heba Badraiq, Liani Devito, Dusko Ilic, Badraiq, Heba, Devito, Liani, Ilic, Dusko

Abstract

From a perspective of manufacturer, procurement of bone marrow aspirates for isolation of mesenchymal stromal/stem cells (MSC) is challenging. The MSC isolated from adult donors have lower proliferation capacity than the cells isolated form young donors of pediatric age. To obtain more MSC from young healthy donors for allogeneic therapy on multiple patients, umbilical cord (UC) seems to be the best alternative. Here, we describe an easy, cost-effective and reproducible protocol of isolation of the MSC from Wharton's Jelly (WJ) in UC.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 5%
Australia 1 5%
Unknown 17 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 21%
Student > Master 3 16%
Student > Ph. D. Student 3 16%
Other 2 11%
Student > Bachelor 2 11%
Other 2 11%
Unknown 3 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 26%
Agricultural and Biological Sciences 5 26%
Chemical Engineering 2 11%
Medicine and Dentistry 1 5%
Materials Science 1 5%
Other 1 5%
Unknown 4 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2014.
All research outputs
#14,657,043
of 22,761,738 outputs
Outputs from Methods in molecular biology
#4,613
of 13,088 outputs
Outputs of similar age
#127,645
of 235,668 outputs
Outputs of similar age from Methods in molecular biology
#19
of 70 outputs
Altmetric has tracked 22,761,738 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,088 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,668 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.