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Cilia

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Attention for Chapter 9: Cilia
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Chapter title
Cilia
Chapter number 9
Book title
Cilia
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3789-9_9
Pubmed ID
Book ISBNs
978-1-4939-3787-5, 978-1-4939-3789-9
Authors

Yuan, Shiaulou, Brueckner, Martina, Shiaulou Yuan, Martina Brueckner

Abstract

Cilia play a key role in the determination of the left-right axis in vertebrates by generating and sensing flow of extraembryonic fluid at the left-right organizer (LRO). Perception of cilia-directed flow triggers a calcium signaling cascade which originates within the cilium itself and then is relayed into the surrounding mesendodermal tissue, thereby directing organ situs via the nodal pathway. Two types of cilia, motile and immotile, function simultaneously to coordinate and direct asymmetric intraciliary calcium signaling cues in the LRO. Here, we describe tools, reagents, and methodologies for the visualization and manipulation of both cilia types as well as intraciliary calcium signaling in the LRO of zebrafish.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 38%
Student > Bachelor 2 25%
Professor 1 13%
Student > Master 1 13%
Researcher 1 13%
Other 0 0%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 50%
Agricultural and Biological Sciences 2 25%
Psychology 1 13%
Neuroscience 1 13%