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Urothelial Carcinoma

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Cover of 'Urothelial Carcinoma'

Table of Contents

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    Book Overview
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    Chapter 1 Analysis of Chromosomal Alterations in Urothelial Carcinoma
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    Chapter 2 Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma
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    Chapter 3 A Versatile Assay for Detection of Aberrant DNA Methylation in Bladder Cancer.
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    Chapter 4 Immunohistochemical Analysis of Urothelial Carcinoma Tissues for Proliferation and Differentiation Markers
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    Chapter 5 Molecular Subtype Profiling of Urothelial Carcinoma Using a Subtype-Specific Immunohistochemistry Panel
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    Chapter 6 Defining the Pathways of Urogenital Schistosomiasis-Associated Urothelial Carcinogenesis through Transgenic and Bladder Wall Egg Injection Models.
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    Chapter 7 Algorithm for the Automated Evaluation of NAT2 Genotypes
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    Chapter 8 Detection of APOBEC3 Proteins and Catalytic Activity in Urothelial Carcinoma
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    Chapter 9 Oxidative Stress in Urothelial Carcinogenesis: Measurements of Protein Carbonylation and Intracellular Production of Reactive Oxygen Species
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    Chapter 10 Urothelial Carcinoma Stem Cells: Current Concepts, Controversies, and Methods.
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    Chapter 11 In Vitro Differentiation and Propagation of Urothelium from Pluripotent Stem Cell Lines.
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    Chapter 12 Spheroid Cultures of Primary Urothelial Cancer Cells: Cancer Tissue-Originated Spheroid (CTOS) Method
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    Chapter 13 The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.
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    Chapter 14 Patient-Derived Bladder Cancer Xenografts
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    Chapter 15 Orthotopic Mouse Models of Urothelial Cancer
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    Chapter 16 Quantification of MicroRNAs in Urine-Derived Specimens.
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    Chapter 17 Quantitative RNA Analysis from Urine Using Real Time PCR
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    Chapter 18 DNA Methylation Analysis from Body Fluids.
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    Chapter 19 Urinary Protein Markers for the Detection and Prognostication of Urothelial Carcinoma
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    Chapter 20 Isolation and Characterization of CTCs from Patients with Cancer of a Urothelial Origin
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    Chapter 21 Epigenetic Treatment Options in Urothelial Carcinoma.
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    Chapter 22 Evaluation of Protein Levels of the Receptor Tyrosine Kinase ErbB3 in Serum
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    Chapter 23 Targeting the PI3K/AKT/mTOR Pathway in Bladder Cancer
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    Chapter 24 Visualization and Quantitative Measurement of Drug-Induced Platinum Adducts in the Nuclear DNA of Individual Cells by an Immuno-Cytological Assay
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    Chapter 25 Erratum to: Urinary Protein Markers for the Detection and Prognostication of Urothelial Carcinoma
Attention for Chapter 15: Orthotopic Mouse Models of Urothelial Cancer
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Chapter title
Orthotopic Mouse Models of Urothelial Cancer
Chapter number 15
Book title
Urothelial Carcinoma
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7234-0_15
Pubmed ID
Book ISBNs
978-1-4939-7233-3, 978-1-4939-7234-0
Authors

Wolfgang Jäger, Igor Moskalev, Peter Raven, Akihiro Goriki, Samir Bidnur, Peter C. Black, Jäger, Wolfgang, Moskalev, Igor, Raven, Peter, Goriki, Akihiro, Bidnur, Samir, Black, Peter C.

Abstract

Orthotopic mouse models of urothelial cancer are essential for testing novel therapies and molecular manipulations of cell lines in vivo. These models are either established by orthotopic inoculation of human (xenograft models) or murine tumor cells (syngeneic models) in immunocompromised or immune competent mice. Current techniques rely on inoculation by intravesical instillation or direct injection into the bladder wall. Alternative models include the induction of murine bladder tumors by chemical carcinogens (BBN) or genetic engineering (GEM).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 18%
Student > Ph. D. Student 2 18%
Lecturer 1 9%
Student > Master 1 9%
Researcher 1 9%
Other 1 9%
Unknown 3 27%
Readers by discipline Count As %
Medicine and Dentistry 2 18%
Agricultural and Biological Sciences 2 18%
Biochemistry, Genetics and Molecular Biology 1 9%
Nursing and Health Professions 1 9%
Unknown 5 45%