Chapter title |
Orthotopic Mouse Models of Urothelial Cancer
|
---|---|
Chapter number | 15 |
Book title |
Urothelial Carcinoma
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7234-0_15 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7233-3, 978-1-4939-7234-0
|
Authors |
Wolfgang Jäger, Igor Moskalev, Peter Raven, Akihiro Goriki, Samir Bidnur, Peter C. Black, Jäger, Wolfgang, Moskalev, Igor, Raven, Peter, Goriki, Akihiro, Bidnur, Samir, Black, Peter C. |
Abstract |
Orthotopic mouse models of urothelial cancer are essential for testing novel therapies and molecular manipulations of cell lines in vivo. These models are either established by orthotopic inoculation of human (xenograft models) or murine tumor cells (syngeneic models) in immunocompromised or immune competent mice. Current techniques rely on inoculation by intravesical instillation or direct injection into the bladder wall. Alternative models include the induction of murine bladder tumors by chemical carcinogens (BBN) or genetic engineering (GEM). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 2 | 18% |
Student > Ph. D. Student | 2 | 18% |
Lecturer | 1 | 9% |
Student > Master | 1 | 9% |
Researcher | 1 | 9% |
Other | 1 | 9% |
Unknown | 3 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 2 | 18% |
Agricultural and Biological Sciences | 2 | 18% |
Biochemistry, Genetics and Molecular Biology | 1 | 9% |
Nursing and Health Professions | 1 | 9% |
Unknown | 5 | 45% |