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Urothelial Carcinoma

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Cover of 'Urothelial Carcinoma'

Table of Contents

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    Book Overview
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    Chapter 1 Analysis of Chromosomal Alterations in Urothelial Carcinoma
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    Chapter 2 Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma
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    Chapter 3 A Versatile Assay for Detection of Aberrant DNA Methylation in Bladder Cancer.
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    Chapter 4 Immunohistochemical Analysis of Urothelial Carcinoma Tissues for Proliferation and Differentiation Markers
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    Chapter 5 Molecular Subtype Profiling of Urothelial Carcinoma Using a Subtype-Specific Immunohistochemistry Panel
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    Chapter 6 Defining the Pathways of Urogenital Schistosomiasis-Associated Urothelial Carcinogenesis through Transgenic and Bladder Wall Egg Injection Models.
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    Chapter 7 Algorithm for the Automated Evaluation of NAT2 Genotypes
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    Chapter 8 Detection of APOBEC3 Proteins and Catalytic Activity in Urothelial Carcinoma
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    Chapter 9 Oxidative Stress in Urothelial Carcinogenesis: Measurements of Protein Carbonylation and Intracellular Production of Reactive Oxygen Species
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    Chapter 10 Urothelial Carcinoma Stem Cells: Current Concepts, Controversies, and Methods.
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    Chapter 11 In Vitro Differentiation and Propagation of Urothelium from Pluripotent Stem Cell Lines.
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    Chapter 12 Spheroid Cultures of Primary Urothelial Cancer Cells: Cancer Tissue-Originated Spheroid (CTOS) Method
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    Chapter 13 The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.
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    Chapter 14 Patient-Derived Bladder Cancer Xenografts
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    Chapter 15 Orthotopic Mouse Models of Urothelial Cancer
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    Chapter 16 Quantification of MicroRNAs in Urine-Derived Specimens.
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    Chapter 17 Quantitative RNA Analysis from Urine Using Real Time PCR
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    Chapter 18 DNA Methylation Analysis from Body Fluids.
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    Chapter 19 Urinary Protein Markers for the Detection and Prognostication of Urothelial Carcinoma
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    Chapter 20 Isolation and Characterization of CTCs from Patients with Cancer of a Urothelial Origin
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    Chapter 21 Epigenetic Treatment Options in Urothelial Carcinoma.
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    Chapter 22 Evaluation of Protein Levels of the Receptor Tyrosine Kinase ErbB3 in Serum
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    Chapter 23 Targeting the PI3K/AKT/mTOR Pathway in Bladder Cancer
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    Chapter 24 Visualization and Quantitative Measurement of Drug-Induced Platinum Adducts in the Nuclear DNA of Individual Cells by an Immuno-Cytological Assay
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    Chapter 25 Erratum to: Urinary Protein Markers for the Detection and Prognostication of Urothelial Carcinoma
Attention for Chapter 2: Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma
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Chapter title
Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma
Chapter number 2
Book title
Urothelial Carcinoma
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7234-0_2
Pubmed ID
Book ISBNs
978-1-4939-7233-3, 978-1-4939-7234-0
Authors

Mustafa Alamyar, Ellen C. Zwarthoff, Alamyar, Mustafa, Zwarthoff, Ellen C.

Abstract

In the last two decades specific point mutations in oncogenes have been identified in urinary bladder cancers. Identification of these mutations in clinical samples (e.g., urine or tumor tissue) can be of use for diagnostic or prognostic purposes. In this chapter we describe how mutations in multiple oncogenes can be identified with a simple assay.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 38%
Student > Doctoral Student 1 13%
Other 1 13%
Student > Ph. D. Student 1 13%
Researcher 1 13%
Other 0 0%
Unknown 1 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 50%
Agricultural and Biological Sciences 2 25%
Medicine and Dentistry 1 13%
Unknown 1 13%