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Mendeley readers
Chapter title |
Tissue-Specific Promoters in the CNS
|
---|---|
Chapter number | 6 |
Book title |
Gene Therapy for Neurological Disorders
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3271-9_6 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3270-2, 978-1-4939-3271-9
|
Authors |
Sebastian Kügler, Kügler, Sebastian |
Abstract |
This chapter outlines some general principles of transcriptional targeting approaches using viral vectors in the central nervous system. Transcriptional targeting is first discussed in the context of vector tropism and appropriate delivery. Then, some of our own attempts to restrict expression of therapeutic factors to distinct brain cell populations are discussed, followed by a detailed description of the setscrews that are available for these experiments. A critical discussion of current stumbling blocks and necessary developments to achieve clinical applicability of advanced targeted vector systems is provided. |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 29% |
Other | 2 | 14% |
Student > Doctoral Student | 2 | 14% |
Student > Bachelor | 2 | 14% |
Student > Master | 1 | 7% |
Other | 2 | 14% |
Unknown | 1 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 6 | 43% |
Agricultural and Biological Sciences | 4 | 29% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Engineering | 1 | 7% |
Unknown | 2 | 14% |