Chapter 1 Technological Issues and Experimental Design of Gene Association Studies

Chapter 2 Statistical Issues in Gene Association Studies

Chapter 3 Identification of Causal Sequence Variants of Disease in the Next Generation Sequencing Era

Chapter 4 Microarray-Based Genome-Wide Association Studies Using Pooled DNA

Chapter 5 Medium-Throughput SNP Genotyping Using Mass Spectrometry: Multiplex SNP Genotyping Using the iPLEX® Gold Assay

Chapter 6 Targeted SNP Genotyping Using the TaqMan® Assay

Chapter 7 Bar-Coded, Multiplexed Sequencing of Targeted DNA Regions Using the Illumina Genome Analyzer

Chapter 8 Site-Directed Mutagenesis

Chapter 9 Gene Expression Profiling of Tissues and Cell Lines: A Dual-Color Microarray Method

Chapter 10 Methods for MicroRNA Microarray Profiling

Chapter 11 Allelic Expression Profiling to Dissect Genome-Wide Association Study Signals

Chapter 12 Quantitative Polymerase Chain Reaction Using the Comparative C q Method

Chapter 14 RNA Mapping Protocols: Northern Blot and Amplification of cDNA Ends

Chapter 15 High-Content RNA Interference Assay: Analysis of Tau Hyperphosphorylation as a Generic Paradigm

Chapter 16 Integrative Systems Biology Approaches to Identify and Prioritize Disease and Drug Candidate Genes

Chapter 17 Identification of a Common Variant Affecting Human Episodic Memory Performance Using a Pooled Genome-Wide Association Approach: A Case Study of Disease Gene Identification

Chapter 18 RNAi-Based Functional Pharmacogenomics

Chapter 19 Genetic Predisposition to β-Thalassemia and Sickle Cell Anemia in Turkey: A Molecular Diagnostic Approach

Chapter 20 Erratum to: Genetic Predisposition to β-Thalassemia and Sickle Cell Anemia in Turkey: A Molecular Diagnostic Approach