| Chapter title |
Diffusion-Weighted Magnetic Resonance Imaging
|
|---|---|
| Chapter number | 6 |
| Book title |
Preclinical MRI
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7531-0_6 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7530-3, 978-1-4939-7531-0
|
| Authors |
Irene Guadilla, Daniel Calle, Pilar López-Larrubia, Guadilla, Irene, Calle, Daniel, López-Larrubia, Pilar |
| Abstract |
Magnetic resonance imaging (MRI) is a technique based on the contents and relaxation features of water in tissues. In basic MRI sequences, diffusion phenomenon of water molecules is not taken into account although it has a notable influence in the relaxation times, and therefore in the signal intensity of images. In fact, MRI techniques that take advantage of water diffusion have experienced a huge development in last years. Diffusion-weighted imaging (DWI) has spectacularly evolved reaching nowadays a great impact both in clinical and preclinical imaging-especially in the neuroimaging field-and in basic research. We present here a protocol to perform DWI studies in a high-field preclinical setup. |
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