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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Elevated expression of LAG-3, but not PD-1, is associated with impaired iNKT cytokine production during chronic HIV-1 infection and treatment
|
|---|---|
| Published in |
Retrovirology, February 2015
|
| DOI | 10.1186/s12977-015-0142-z |
| Pubmed ID | |
| Authors |
Jennifer A Juno, Andrew T Stalker, Jillian LM Waruk, Julius Oyugi, Makobu Kimani, Francis A Plummer, Joshua Kimani, Keith R Fowke |
| Abstract |
LAG-3 is a potent negative regulator of the immune response but its impact in HIV infection in poorly understood. Unlike exhaustion markers such as PD-1, Tim-3, 2B4 and CD160, LAG-3 is poorly expressed on bulk and antigen-specific T cells during chronic HIV infection and its expression on innate lymphocyte subsets is not well understood. The aim of this study was to assess LAG-3 expression and association with cellular dysfunction on T cells, NK cells and iNKT cells among a cohort of healthy and HIV-infected female sex workers in Nairobi, Kenya. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 67 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 24% |
| Student > Master | 13 | 19% |
| Researcher | 12 | 18% |
| Student > Bachelor | 8 | 12% |
| Other | 5 | 7% |
| Other | 7 | 10% |
| Unknown | 7 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 20 | 29% |
| Agricultural and Biological Sciences | 14 | 21% |
| Medicine and Dentistry | 11 | 16% |
| Biochemistry, Genetics and Molecular Biology | 6 | 9% |
| Linguistics | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 10 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2015.
All research outputs
#15,322,526
of 22,789,566 outputs
Outputs from Retrovirology
#780
of 1,106 outputs
Outputs of similar age
#213,939
of 358,519 outputs
Outputs of similar age from Retrovirology
#15
of 17 outputs
Altmetric has tracked 22,789,566 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 358,519 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.