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Mendeley readers
Attention Score in Context
| Title |
Clinical applications of mesenchymal stem cells
|
|---|---|
| Published in |
Journal of Hematology & Oncology, April 2012
|
| DOI | 10.1186/1756-8722-5-19 |
| Pubmed ID | |
| Authors |
Shihua Wang, Xuebin Qu, Robert Chunhua Zhao |
| Abstract |
Mesenchymal stem cells (MSC) have generated a great amount of enthusiasm over the past decade as a novel therapeutic paradigm for a variety of diseases. Currently, MSC based clinical trials have been conducted for at least 12 kinds of pathological conditions, with many completed trials demonstrating the safety and efficacy. This review provides an overview of the recent clinical findings related to MSC therapeutic effects. Roles of MSCs in clinical trials conducted to treat graft-versus-host-disease (GVHD) and cardiovascular diseases are highlighted. Clinical application of MSC are mainly attributed to their important four biological properties- the ability to home to sites of inflammation following tissue injury when injected intravenously; to differentiate into various cell types; to secrete multiple bioactive molecules capable of stimulating recovery of injured cells and inhibiting inflammation and to perform immunomodulatory functions. Here, we will discuss these four properties. Moreover, the issues surrounding clinical grade MSCs and principles for MSC therapeutic approaches are also addressed on the transition of MSCs therapy from bench side to bedside. |
Mendeley readers
The data shown below were compiled from readership statistics for 460 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | <1% |
| Turkey | 2 | <1% |
| Uruguay | 1 | <1% |
| Brazil | 1 | <1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| Sweden | 1 | <1% |
| Japan | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 448 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 87 | 19% |
| Student > Master | 77 | 17% |
| Student > Bachelor | 67 | 15% |
| Researcher | 53 | 12% |
| Student > Doctoral Student | 20 | 4% |
| Other | 56 | 12% |
| Unknown | 100 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 113 | 25% |
| Medicine and Dentistry | 75 | 16% |
| Biochemistry, Genetics and Molecular Biology | 69 | 15% |
| Engineering | 28 | 6% |
| Immunology and Microbiology | 9 | 2% |
| Other | 51 | 11% |
| Unknown | 115 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2024.
All research outputs
#1,676,810
of 22,790,780 outputs
Outputs from Journal of Hematology & Oncology
#95
of 1,191 outputs
Outputs of similar age
#10,449
of 162,753 outputs
Outputs of similar age from Journal of Hematology & Oncology
#2
of 9 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,191 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 162,753 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.