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Mendeley readers
Attention Score in Context
| Title |
MicroRNAs and their target gene networks in breast cancer
|
|---|---|
| Published in |
Breast Cancer Research, March 2010
|
| DOI | 10.1186/bcr2484 |
| Pubmed ID | |
| Authors |
Elizabeth O'Day, Ashish Lal |
| Abstract |
MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that post-transcriptionally inhibit gene expression. Many miRNAs have been implicated in several human cancers, including breast cancer. Here we describe the association between altered miRNA signatures and breast cancer tumorigenesis and metastasis. The loss of several tumor suppressor miRNAs (miR-206, miR-17-5p, miR-125a, miR-125b, miR-200, let-7, miR-34 and miR-31) and the overexpression of certain oncogenic miRNAs (miR-21, miR-155, miR-10b, miR-373 and miR-520c) have been observed in many breast cancers. The gene networks orchestrated by these miRNAs are still largely unknown, although key targets have been identified that may contribute to the disease phenotype. Here we report how the observed perturbations in miRNA expression profiles may lead to disruption of key pathways involved in breast cancer. |
Mendeley readers
The data shown below were compiled from readership statistics for 371 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 1% |
| Argentina | 2 | <1% |
| Netherlands | 2 | <1% |
| Portugal | 1 | <1% |
| Malaysia | 1 | <1% |
| Norway | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Latvia | 1 | <1% |
| Germany | 1 | <1% |
| Other | 8 | 2% |
| Unknown | 348 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 90 | 24% |
| Researcher | 75 | 20% |
| Student > Master | 59 | 16% |
| Student > Bachelor | 30 | 8% |
| Student > Doctoral Student | 24 | 6% |
| Other | 57 | 15% |
| Unknown | 36 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 148 | 40% |
| Biochemistry, Genetics and Molecular Biology | 72 | 19% |
| Medicine and Dentistry | 63 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 2% |
| Engineering | 7 | 2% |
| Other | 28 | 8% |
| Unknown | 46 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2013.
All research outputs
#5,446,210
of 25,371,288 outputs
Outputs from Breast Cancer Research
#643
of 2,052 outputs
Outputs of similar age
#22,536
of 103,050 outputs
Outputs of similar age from Breast Cancer Research
#3
of 11 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,050 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.