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Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population

Overview of attention for article published in Journal of Translational Medicine, February 2015
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  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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Title
Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population
Published in
Journal of Translational Medicine, February 2015
DOI 10.1186/s12967-015-0411-6
Pubmed ID
Authors

Rohit Upadhyay, Amal Robay, Khalid Fakhro, Charbel Abi Khadil, Mahmoud Zirie, Amin Jayyousi, Maha El-Shafei, Szilard Kiss, Donald J D′Amico, Jacqueline Salit, Michelle R Staudt, Sarah L O′Beirne, Xiaoliang Chen, Balwant Tuana, Ronald G Crystal, Hong Ding

Abstract

Overexpression of SLMAP gene has been associated with diabetes and endothelial dysfunction of macro- and micro-blood vessels. In this study our primary objective is to explore the role of SLMAP gene polymorphisms in the susceptibility of type 2 diabetes (T2DM) with or without diabetic retinopathy (DR) in the Qatari population. A total of 342 Qatari subjects (non-diabetic controls and T2DM patients with or without DR) were genotyped for SLMAP gene polymorphisms (rs17058639 C > T; rs1043045 C > T and rs1057719 A > G) using Taqman SNP genotyping assay. SLMAP rs17058639 C > T polymorphism was associated with the presence of DR among Qataris with T2DM. One-way ANOVA and multiple logistic regression analysis showed SLMAP SNP rs17058639 C > T as an independent risk factor for DR development. SLMAP rs17058639 C > T polymorphism also had a predictive role for the severity of DR. Haplotype Crs17058639Trs1043045Ars1057719 was associated with the increased risk for DR among Qataris with T2DM. The data suggests the potential role of SLMAP SNPs as a risk factor for the susceptibility of DR among T2DM patients in the Qatari population.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 11%
Student > Master 3 11%
Student > Ph. D. Student 2 7%
Student > Postgraduate 2 7%
Student > Bachelor 1 4%
Other 5 19%
Unknown 11 41%
Readers by discipline Count As %
Medicine and Dentistry 8 30%
Agricultural and Biological Sciences 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Computer Science 2 7%
Neuroscience 1 4%
Other 0 0%
Unknown 12 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2015.
All research outputs
#13,194,629
of 22,790,780 outputs
Outputs from Journal of Translational Medicine
#1,521
of 3,988 outputs
Outputs of similar age
#185,009
of 385,323 outputs
Outputs of similar age from Journal of Translational Medicine
#45
of 118 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,988 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 385,323 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.