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Increased risk of venous thrombosis by AB alleles of the ABO blood group and Factor V Leiden in a Brazilian population

Overview of attention for article published in Genetics and Molecular Biology, June 2009
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Title
Increased risk of venous thrombosis by AB alleles of the ABO blood group and Factor V Leiden in a Brazilian population
Published in
Genetics and Molecular Biology, June 2009
DOI 10.1590/s1415-47572009000200010
Pubmed ID
Authors

Magaly B.P.L.V. Lima, Aldemir Branco de Oliveira-Filho, Júlia F. Campos, Fárida C.B.C. Melo, Washington Batista das Neves, Raul Antônio Morais Melo, José Alexandre Rodrigues Lemos

Abstract

Most cases of a predisposition to venous thrombosis are caused by resistance to activated protein C, associated in 95% of cases with the Factor V Leiden allele (FVL or R506Q). Several recent studies report a further increased risk of thrombosis by an association between the AB alleles of the ABO blood group and Factor V Leiden. The present study investigated this association with deep vein thrombosis (DVT) in individuals treated at the Hemocentro de Pernambuco in northeastern Brazil. A case-control comparison showed a significant risk of thrombosis in the presence of Factor V Leiden (OR = 10.1), which was approximately doubled when the AB alleles of the ABO blood group were present as well (OR = 22.3). These results confirm that the increased risk of deep vein thrombosis in the combined presence of AB alleles and Factor V Leiden is also applicable to the Brazilian population suggesting that ABO blood group typing should be routinely added to FVL in studies involving thrombosis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 3 12%
Unknown 23 88%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 5 19%
Other 4 15%
Student > Bachelor 3 12%
Researcher 3 12%
Professor > Associate Professor 3 12%
Other 4 15%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 15 58%
Agricultural and Biological Sciences 4 15%
Biochemistry, Genetics and Molecular Biology 2 8%
Design 1 4%
Unknown 4 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2015.
All research outputs
#17,236,404
of 25,374,647 outputs
Outputs from Genetics and Molecular Biology
#406
of 771 outputs
Outputs of similar age
#107,246
of 125,220 outputs
Outputs of similar age from Genetics and Molecular Biology
#6
of 7 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 771 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,220 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.