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Increased risk of venous thrombosis by AB alleles of the ABO blood group and Factor V Leiden in a Brazilian population

Overview of attention for article published in Genetics and Molecular Biology, January 2009
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Title
Increased risk of venous thrombosis by AB alleles of the ABO blood group and Factor V Leiden in a Brazilian population
Published in
Genetics and Molecular Biology, January 2009
DOI 10.1590/s1415-47572009000200010
Pubmed ID
Authors

Magaly B.P.L.V. Lima, Aldemir Branco de Oliveira-Filho, Júlia F. Campos, Fárida C.B.C. Melo, Washington Batista das Neves, Raul Antônio Morais Melo, José Alexandre Rodrigues Lemos

Abstract

Most cases of a predisposition to venous thrombosis are caused by resistance to activated protein C, associated in 95% of cases with the Factor V Leiden allele (FVL or R506Q). Several recent studies report a further increased risk of thrombosis by an association between the AB alleles of the ABO blood group and Factor V Leiden. The present study investigated this association with deep vein thrombosis (DVT) in individuals treated at the Hemocentro de Pernambuco in northeastern Brazil. A case-control comparison showed a significant risk of thrombosis in the presence of Factor V Leiden (OR = 10.1), which was approximately doubled when the AB alleles of the ABO blood group were present as well (OR = 22.3). These results confirm that the increased risk of deep vein thrombosis in the combined presence of AB alleles and Factor V Leiden is also applicable to the Brazilian population suggesting that ABO blood group typing should be routinely added to FVL in studies involving thrombosis.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 3 16%
Unknown 16 84%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 5 26%
Professor > Associate Professor 3 16%
Researcher 3 16%
Other 2 11%
Student > Bachelor 2 11%
Other 4 21%
Readers by discipline Count As %
Medicine and Dentistry 13 68%
Agricultural and Biological Sciences 4 21%
Biochemistry, Genetics and Molecular Biology 1 5%
Design 1 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2015.
All research outputs
#8,110,276
of 12,982,601 outputs
Outputs from Genetics and Molecular Biology
#145
of 290 outputs
Outputs of similar age
#113,555
of 215,063 outputs
Outputs of similar age from Genetics and Molecular Biology
#4
of 7 outputs
Altmetric has tracked 12,982,601 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 290 research outputs from this source. They receive a mean Attention Score of 2.1. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 215,063 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.