Title |
Does vitamin D play a significant role in type 2 diabetes?
|
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Published in |
BMC Endocrine Disorders, February 2015
|
DOI | 10.1186/s12902-015-0003-8 |
Pubmed ID | |
Authors |
Jayesh J Sheth, Ankna Shah, Frenny J Sheth, Sunil Trivedi, Mamta Lele, Navneet Shah, Premal Thakor, Rama Vaidya |
Abstract |
Vitamin D deficiency reportedly is associated with type 2 diabetes (T2DM). We aim to examine whether 25-hydroxyvitamin D (25OHD) has clinically significant influence on hemoglobin glycation (HbA1c) and insulin resistance (HOMA-IR) in T2DM subjects. Present study was carried out in 912 subjects (429 T2DM cases and 483 non-diabetic controls) from Western India. The enrolled study subjects were investigated for biochemical parameters like FBS, PPBS, HbA1c, FI, HOMA-IR and 25OHD levels in blood. Vitamin D deficiency was seen in 91.4% and 93.0% of T2DM cases and control subjects respectively. There was no association of serum 25OHD deficiency on HbA1c or HOMA-IR in T2DM cases (p = 0.057 & p = 0.257 respectively) and in control subjects (p = 0.675 & p = 0.647 respectively). Our findings suggests that though vitamin D deficiency is prevalent in T2DM and non-diabetic subjects, its role in hemoglobin glycation and insulin resistance could not be established. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | 50% |
India | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 83 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 9 | 11% |
Student > Ph. D. Student | 6 | 7% |
Student > Postgraduate | 6 | 7% |
Student > Master | 6 | 7% |
Professor | 5 | 6% |
Other | 19 | 23% |
Unknown | 32 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 22% |
Nursing and Health Professions | 9 | 11% |
Biochemistry, Genetics and Molecular Biology | 6 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
Agricultural and Biological Sciences | 5 | 6% |
Other | 5 | 6% |
Unknown | 35 | 42% |