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Cigarette smoking: an important renal risk factor – far beyond carcinogenesis

Overview of attention for article published in Tobacco Induced Diseases, June 2002
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  • Above-average Attention Score compared to outputs of the same age (55th percentile)

Mentioned by

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2 tweeters

Citations

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35 Dimensions

Readers on

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45 Mendeley
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Title
Cigarette smoking: an important renal risk factor – far beyond carcinogenesis
Published in
Tobacco Induced Diseases, June 2002
DOI 10.1186/1617-9625-1-2-137
Pubmed ID
Authors

Orth, S R

Abstract

In recent years, it has become apparent that smoking has a negative impact on renal function, being one of the most important remediable renal risk factors. It has been clearly shown that the risk for high-normal urinary albumin excretion and microalbuminuria is increased in smoking compared to non-smoking subjects of the general population. Data from the Multiple Risk Factor Intervention Trial (MRFIT) indicate that at least in males, smoking increases the risk to reach end-stage renal failure. Smoking is particularly "nephrotoxic" in older subjects, subjects with essential hypertension and patients with preexisting renal disease. Of interest, the magnitude of the adverse renal effect of smoking seems to be independent of the underlying renal disease. Death-censored renal graft survival is decreased in smokers, indicating that smoking also damages the renal transplant. Cessation of smoking has been show to reduce the rate of progression of renal failure both in patients with renal disease or a renal transplant. The mechanisms of smoking-induced renal damage are only partly understood and comprise acute hemodynamic (e.g., increase in blood pressure and presumably intraglomerular pressure) and chronic effects (e.g., endothelial cell dysfunction). Renal failure per se leads to an increased cardiovascular risk. The latter is further aggravated by smoking. Particularly survival of smokers with diabetes mellitus on hemodialysis is abysmal. In the present review article the current state of knowledge about the renal risks of smoking is reviewed. It is the aim of the article to point out that smoking not only increases the risk of renal cell carcinoma or uroepithelial cell carcinoma, but also the risk of a faster decline of renal function. The latter is a relatively new negative aspect which has not been widely recognized.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 16%
Student > Postgraduate 7 16%
Researcher 7 16%
Student > Bachelor 5 11%
Student > Ph. D. Student 4 9%
Other 5 11%
Unknown 10 22%
Readers by discipline Count As %
Medicine and Dentistry 20 44%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Biochemistry, Genetics and Molecular Biology 2 4%
Nursing and Health Professions 2 4%
Agricultural and Biological Sciences 2 4%
Other 4 9%
Unknown 13 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2015.
All research outputs
#2,098,985
of 4,868,490 outputs
Outputs from Tobacco Induced Diseases
#46
of 96 outputs
Outputs of similar age
#61,965
of 145,009 outputs
Outputs of similar age from Tobacco Induced Diseases
#2
of 2 outputs
Altmetric has tracked 4,868,490 research outputs across all sources so far. This one has received more attention than most of these and is in the 55th percentile.
So far Altmetric has tracked 96 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 145,009 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.