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Mendeley readers
| Title |
TNF-α augmented Porphyromonas gingivalis invasion in human gingival epithelial cells through Rab5 and ICAM-1
|
|---|---|
| Published in |
BMC Microbiology, September 2014
|
| DOI | 10.1186/s12866-014-0229-z |
| Pubmed ID | |
| Authors |
Yoshiko Kato, Makoto Hagiwara, Yuichi Ishihara, Ryutaro Isoda, Shinsuke Sugiura, Toshinori Komatsu, Naoyuki Ishida, Toshihide Noguchi, Kenji Matsushita |
| Abstract |
Tumor necrosis factor alpha (TNF-α) plays a central role in the initiation and maintenance of immune responses to periodontopathic bacteria. However, excess TNF-α leads to dysregulated immune responses and progression of periodontitis. Porphyromonas gingivalis (P. gingivalis) invades gingival epithelial cells and then multiplies and survives for a long period. Additionally, increment of TNF-α in periodontal sites is associated with a high prevalence of gram-negative anaerobes such as P. gingivalis. However, it has not been determined whether TNF-α affects invasion of P. gingivalis in periodontal tissues. |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 4% |
| Unknown | 26 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 5 | 19% |
| Student > Master | 4 | 15% |
| Researcher | 4 | 15% |
| Student > Ph. D. Student | 2 | 7% |
| Student > Bachelor | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 7 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 26% |
| Agricultural and Biological Sciences | 6 | 22% |
| Immunology and Microbiology | 4 | 15% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Engineering | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 8 | 30% |