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Mitochondrial and sex steroid hormone crosstalk during aging

Overview of attention for article published in Longevity & Healthspan, February 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)

Mentioned by

5 tweeters
1 Google+ user


53 Dimensions

Readers on

85 Mendeley
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Mitochondrial and sex steroid hormone crosstalk during aging
Published in
Longevity & Healthspan, February 2014
DOI 10.1186/2046-2395-3-2
Pubmed ID

Michael C Velarde


Decline in circulating sex steroid hormones accompanies several age-associated pathologies which may influence human healthspan. Mitochondria play important roles in biosynthesis of sex steroid hormones, and these hormones can also regulate mitochondrial function. Understanding the cross talk between mitochondria and sex steroid hormones may provide insights into the pathologies associated with aging. The aim of this review is to summarize the current knowledge regarding the interplay between mitochondria and sex steroid hormones during the aging process. The review describes the effect of mitochondria on sex steroid hormone production in the gonads, and then enumerates the contribution of sex steroid hormones on mitochondrial function in hormone responsive cells. Decline in sex steroid hormones and accumulation of mitochondrial damage may create a positive feedback loop that contributes to the progressive degeneration in tissue function during aging. The review further speculates whether regulation between mitochondrial function and sex steroid hormone action can potentially influence healthspan.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Unknown 83 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 24%
Student > Ph. D. Student 19 22%
Student > Master 10 12%
Student > Bachelor 10 12%
Student > Doctoral Student 7 8%
Other 14 16%
Unknown 5 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 24%
Medicine and Dentistry 20 24%
Biochemistry, Genetics and Molecular Biology 18 21%
Neuroscience 5 6%
Nursing and Health Professions 4 5%
Other 10 12%
Unknown 8 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2020.
All research outputs
of 15,748,935 outputs
Outputs from Longevity & Healthspan
of 24 outputs
Outputs of similar age
of 218,647 outputs
Outputs of similar age from Longevity & Healthspan
of 1 outputs
Altmetric has tracked 15,748,935 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 24 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.3. This one scored the same or higher as 7 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 218,647 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them