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Anti-Oxidant and Anti-Hypercholesterolemic Activities ofWasabia japonica

Overview of attention for article published in Evidence-based Complementary & Alternative Medicine (eCAM), January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

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2 news outlets
twitter
1 tweeter

Citations

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17 Dimensions

Readers on

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11 Mendeley
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Title
Anti-Oxidant and Anti-Hypercholesterolemic Activities ofWasabia japonica
Published in
Evidence-based Complementary & Alternative Medicine (eCAM), January 2010
DOI 10.1093/ecam/nen038
Pubmed ID
Authors

Young Sun Lee, Jae Ha Yang, Man Jong Bae, Wang Keun Yoo, Shen Ye, Charlie C. L. Xue, Chun Guang Li

Abstract

The effects of Wasabia japonica (WJ) were investigated in vitro and in vivo for their anti-oxidant and anti-hypercholesterolemic activities. It was found that the aqueous extracts of WJ leaves (WJL) had strong scavenging activities towards 1,1-Diphenyl-2-picryhydrazyl (DPPH) and nitric oxide (NO) free radicals in cell free systems. WJL also inhibited NO production and the expressions of inducible NO synthase (iNOS) mRNA and enzyme protein, determined by Griess reactions, RT-PCR or Western blotting respectively in Lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages cells. The anti-hypercholesterolemic effects of WJ diet were investigated in hypercholesterolemia rats. Sprague-Dawley rats were divided into four groups and were fed with either normal diet (Group 1), or diet containing 1%(w/w) cholesterol (Groups 2, 3 and 4). After 4 weeks, Group 2 was changed to normal diet, Groups 3 and 4 were changed to the diet containing 5% WJ leaf and or 5% WJ root, respectively. 3 weeks after WJ diets, Serum HDL-cholesterol levels were significantly increased in WJ diet groups compared with the normal diet hypercholesterolemia rats. In contrast, the serum LDL-cholesterol levels and liver xanthine oxidase (XO) activity in WJ diet groups were significantly decreased. The results indicate that the WJ extracts have significant anti-oxidant activities, and the WJ diet exhibited anti-hypercholesterolemic action in high cholesterol diet rats, which was companied with modulations of cholesterol metabolism and decrease in liver XO activity.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 9%
Unknown 10 91%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 45%
Researcher 2 18%
Student > Ph. D. Student 1 9%
Student > Bachelor 1 9%
Professor > Associate Professor 1 9%
Other 0 0%
Unknown 1 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 36%
Medicine and Dentistry 3 27%
Social Sciences 1 9%
Chemistry 1 9%
Nursing and Health Professions 1 9%
Other 0 0%
Unknown 1 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2019.
All research outputs
#871,132
of 13,361,190 outputs
Outputs from Evidence-based Complementary & Alternative Medicine (eCAM)
#302
of 5,735 outputs
Outputs of similar age
#6,067
of 96,327 outputs
Outputs of similar age from Evidence-based Complementary & Alternative Medicine (eCAM)
#1
of 2 outputs
Altmetric has tracked 13,361,190 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,735 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 96,327 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them