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Regulation of microRNA expression and function by nuclear receptor signaling

Overview of attention for article published in Cell & Bioscience, September 2011
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Title
Regulation of microRNA expression and function by nuclear receptor signaling
Published in
Cell & Bioscience, September 2011
DOI 10.1186/2045-3701-1-31
Pubmed ID
Authors

Zhihong Yang, Li Wang

Abstract

MicroRNAs (miRNAs) are small non-coding RNA transcripts that affect various cellular pathways by serving as regulators of gene expression at the translational and transcriptional level. Nuclear receptors (NRs) are ligand-activated transcription factors that regulate gene transcription by binding to the promoter region or by interacting with other transcription factors. NRs can regulate miRNA expression either at the transcriptional level, or through posttranscriptional maturation by interacting with miRNA processing factors. This review will summarize recent advances in knowledge of the modulation of miRNA expression by NRs. Increased understanding of the molecular basis of miRNA expression may enable new therapeutic interventions that modulate miRNA activities through NR-mediated signaling.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Pakistan 1 1%
Sweden 1 1%
India 1 1%
Denmark 1 1%
United States 1 1%
Unknown 89 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 21%
Student > Ph. D. Student 19 20%
Student > Master 16 17%
Student > Bachelor 11 12%
Student > Doctoral Student 10 11%
Other 12 13%
Unknown 7 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 39 41%
Biochemistry, Genetics and Molecular Biology 22 23%
Medicine and Dentistry 7 7%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Neuroscience 4 4%
Other 6 6%
Unknown 13 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2011.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Cell & Bioscience
#697
of 1,177 outputs
Outputs of similar age
#118,323
of 141,254 outputs
Outputs of similar age from Cell & Bioscience
#7
of 7 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,177 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,254 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.