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BACE1 inhibitory activity of fungal endophytic extracts from Malaysian medicinal plants

Overview of attention for article published in BMC Complementary and Alternative Medicine, September 2011
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1 tweeter

Citations

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50 Mendeley
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Title
BACE1 inhibitory activity of fungal endophytic extracts from Malaysian medicinal plants
Published in
BMC Complementary and Alternative Medicine, September 2011
DOI 10.1186/1472-6882-11-79
Pubmed ID
Authors

Azzeme Harun, Richard Muhammad Johari James, Siong Meng Lim, Abu Bakar Abdul Majeed, Anthony LJ Cole, Kalavathy Ramasamy

Abstract

BACE1 was found to be the major β-secretase in neurons and its appearance and activity were found to be elevated in the brains of AD patients. Fungal endophytic extracts for BACE1 inhibitory activity and cytotoxicity against PC-12 (a rat pheochromocytoma with neuronal properties) and WRL68 (a non-tumorigenic human hepatic) were investigated.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
United States 1 2%
Australia 1 2%
Unknown 47 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 22%
Student > Master 8 16%
Researcher 7 14%
Lecturer 4 8%
Student > Bachelor 4 8%
Other 13 26%
Unknown 3 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 44%
Medicine and Dentistry 5 10%
Chemistry 5 10%
Biochemistry, Genetics and Molecular Biology 3 6%
Immunology and Microbiology 2 4%
Other 8 16%
Unknown 5 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2011.
All research outputs
#9,906,033
of 12,373,180 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,741
of 2,511 outputs
Outputs of similar age
#75,330
of 95,567 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#23
of 24 outputs
Altmetric has tracked 12,373,180 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,511 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,567 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.