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Molecular insights into land snail neuropeptides through transcriptome and comparative gene analysis

Overview of attention for article published in BMC Genomics, April 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

Mentioned by

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4 tweeters

Citations

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37 Dimensions

Readers on

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48 Mendeley
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Title
Molecular insights into land snail neuropeptides through transcriptome and comparative gene analysis
Published in
BMC Genomics, April 2015
DOI 10.1186/s12864-015-1510-8
Pubmed ID
Authors

Kevin J Adamson, Tianfang Wang, Min Zhao, Francesca Bell, Anna V Kuballa, Kenneth B Storey, Scott F Cummins

Abstract

Snails belong to the molluscan class Gastropoda, which inhabit land, freshwater and marine environments. Several land snail species, including Theba pisana, are crop pests of major concern, causing extensive damage to agriculture and horticulture. A deeper understanding of their molecular biology is necessary in order to develop methods to manipulate land snail populations. The present study used in silico gene data mining of T. pisana tissue transcriptomes to predict 24,920 central nervous system (CNS) proteins, 37,661 foot muscle proteins and 40,766 hepatopancreas proteins, which together have 5,236 unique protein functional domains. Neuropeptides, metabolic enzymes and epiphragmin genes dominated expression within the CNS, hepatopancreas and muscle, respectively. Further investigation of the CNS transcriptome demonstrated that it might contain as many as 5,504 genes that encode for proteins destined for extracellular secretion. Neuropeptides form an important class of cell-cell messengers that control or influence various complex metabolic events. A total of 35 full-length neuropeptide genes were abundantly expressed within T. pisana CNS, encoding precursors that release molluscan-type bioactive neuropeptide products. These included achatin, allototropin, conopressin, elevenin, FMRFamide, LFRFamide, LRFNVamide, myomodulins, neurokinin Y, PKYMDT, PXFVamide, sCAPamides and several insulin-like peptides. Liquid chromatography-mass spectrometry of neural ganglia confirmed the presence of many of these neuropeptides. Our results provide the most comprehensive picture of the molecular genes and proteins associated with land snail functioning, including the repertoire of neuropeptides that likely play significant roles in neuroendocrine signalling. This information has the potential to expedite the study of molluscan metabolism and potentially stimulate advances in the biological control of land snail pest species.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Chile 1 2%
Sweden 1 2%
Canada 1 2%
Unknown 44 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 27%
Student > Ph. D. Student 10 21%
Student > Master 7 15%
Student > Bachelor 3 6%
Student > Doctoral Student 3 6%
Other 5 10%
Unknown 7 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 44%
Biochemistry, Genetics and Molecular Biology 9 19%
Neuroscience 4 8%
Immunology and Microbiology 3 6%
Nursing and Health Professions 1 2%
Other 2 4%
Unknown 8 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2015.
All research outputs
#1,179,305
of 5,058,381 outputs
Outputs from BMC Genomics
#1,231
of 4,605 outputs
Outputs of similar age
#49,138
of 154,016 outputs
Outputs of similar age from BMC Genomics
#90
of 199 outputs
Altmetric has tracked 5,058,381 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,605 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 154,016 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 199 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.