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High relative abundance of firmicutes and increased TNF-α levels correlate with obesity in children

Overview of attention for article published in Salud publica de Mexico, December 2017
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Title
High relative abundance of firmicutes and increased TNF-α levels correlate with obesity in children
Published in
Salud publica de Mexico, December 2017
DOI 10.21149/8133
Pubmed ID
Authors

Yaneth C Orbe-Orihuela, Alfredo Lagunas-Martínez, Margarita Bahena-Román, Vicente Madrid-Marina, Kirvis Torres-Poveda, Eugenia Flores-Alfaro, Araceli Méndez-Padrón, Cinthya E Díaz-Benítez, Oscar Peralta-Zaragoza, Diana Antúnez-Ortiz, Miguel Cruz, Ana I Burguete-García

Abstract

To investigate the correlation among pro- or anti-inflammatory cytokines and the two main gut microbiota phyla in obese children. Anthropometric data were obtained from 890 children under 14 years old to determine the degree of obesity. Serum cytokine concentration was measured by ELISA. Relative abundance of gut microbiota in feces was evaluated by quantitative RealTime PCR assays. Anthropometric and biochemical parameters were statistically higher in overweigth/ obese children (OW/O) than in lean (NW), Increased TNF-α levels were found in obese children that also have a high relative abundance of Firmicutes. Obese children have a high relative abundance of Firmicutes that correlates with increased levels of TNF-α. This is the first study that shows a relation between Firmicute abundance and TNF-α serum concentration in obese children.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 98 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 19%
Student > Master 15 15%
Researcher 13 13%
Student > Ph. D. Student 11 11%
Student > Postgraduate 5 5%
Other 13 13%
Unknown 22 22%
Readers by discipline Count As %
Medicine and Dentistry 17 17%
Nursing and Health Professions 13 13%
Biochemistry, Genetics and Molecular Biology 12 12%
Agricultural and Biological Sciences 8 8%
Sports and Recreations 4 4%
Other 14 14%
Unknown 30 31%