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Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients with sepsis-associated acute kidney…

Overview of attention for article published in Critical Care, May 2015
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Mentioned by

twitter
2 tweeters
facebook
1 Facebook page

Citations

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55 Dimensions

Readers on

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55 Mendeley
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Title
Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients with sepsis-associated acute kidney injury
Published in
Critical Care, May 2015
DOI 10.1186/s13054-015-0941-6
Pubmed ID
Authors

Xingui Dai, Zhenhua Zeng, Chunlai Fu, Sheng’an Zhang, Yeping Cai, Zhongqing Chen

Abstract

Neutrophil gelatinase-associated lipocalin (NGAL), cystatin (Cys)-C, and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic biomarkers of acute kidney injury (AKI). We aimed to determine the diagnostic properties of these biomarkers for detecting AKI in critically ill patients with sepsis. We divided 112 septic patients into the non-AKI sepsis (n = 57) and AKI sepsis (n = 55) group. Plasma and urine specimens were collected on admission and every 24 h until 72 h and tested for NGAL, Cys-C, and TREM-1 concentrations. Their levels were compared on admission, at diagnosis and 24 h before diagnosis. Both plasma and urine NGAL, Cys-C and sTREM-1 were significantly associated with AKI development in septic patients, even after adjustment for confounders using generalized estimating equations (GEEs). Compared with the non-AKI sepsis group, the sepsis AKI group exhibited markedly higher levels of these biomarkers at diagnosis and 24 h before AKI diagnosis (P < 0.01). The diagnostic and predictive values of plasma and urine NGAL were good, and those of plasma and urine Cys-C and sTREM-1 were fair. Plasma and urine NGAL, Cys-C, and sTREM-1 can be used as diagnostic and predictive biomarkers for AKI in critically ill patients with sepsis.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Brazil 1 2%
Unknown 53 96%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 10 18%
Researcher 9 16%
Student > Ph. D. Student 9 16%
Student > Master 4 7%
Professor 3 5%
Other 12 22%
Unknown 8 15%
Readers by discipline Count As %
Medicine and Dentistry 34 62%
Agricultural and Biological Sciences 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Nursing and Health Professions 2 4%
Neuroscience 2 4%
Other 3 5%
Unknown 9 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2015.
All research outputs
#7,710,313
of 12,786,839 outputs
Outputs from Critical Care
#3,198
of 4,101 outputs
Outputs of similar age
#111,398
of 226,743 outputs
Outputs of similar age from Critical Care
#7
of 13 outputs
Altmetric has tracked 12,786,839 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.3. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,743 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.