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Mediterranean Diet and Age-Related Cognitive Decline

Overview of attention for article published in JAMA Internal Medicine, July 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#45 of 4,061)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Citations

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315 Dimensions

Readers on

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418 Mendeley
Title
Mediterranean Diet and Age-Related Cognitive Decline
Published in
JAMA Internal Medicine, July 2015
DOI 10.1001/jamainternmed.2015.1668
Pubmed ID
Authors

Cinta Valls-Pedret, Aleix Sala-Vila, Mercè Serra-Mir, Dolores Corella, Rafael de la Torre, Miguel Ángel Martínez-González, Elena H. Martínez-Lapiscina, Montserrat Fitó, Ana Pérez-Heras, Jordi Salas-Salvadó, Ramon Estruch, Emilio Ros

Abstract

Oxidative stress and vascular impairment are believed to partly mediate age-related cognitive decline, a strong risk factor for development of dementia. Epidemiologic studies suggest that a Mediterranean diet, an antioxidant-rich cardioprotective dietary pattern, delays cognitive decline, but clinical trial evidence is lacking. To investigate whether a Mediterranean diet supplemented with antioxidant-rich foods influences cognitive function compared with a control diet. Parallel-group randomized clinical trial of 447 cognitively healthy volunteers from Barcelona, Spain (233 women [52.1%]; mean age, 66.9 years), at high cardiovascular risk were enrolled into the Prevención con Dieta Mediterránea nutrition intervention trial from October 1, 2003, through December 31, 2009. All patients underwent neuropsychological assessment at inclusion and were offered retesting at the end of the study. Participants were randomly assigned to a Mediterranean diet supplemented with extravirgin olive oil (1 L/wk), a Mediterranean diet supplemented with mixed nuts (30 g/d), or a control diet (advice to reduce dietary fat). Rates of cognitive change over time based on a neuropsychological test battery: Mini-Mental State Examination, Rey Auditory Verbal Learning Test (RAVLT), Animals Semantic Fluency, Digit Span subtest from the Wechsler Adult Intelligence Scale, Verbal Paired Associates from the Wechsler Memory Scale, and the Color Trail Test. We used mean z scores of change in each test to construct 3 cognitive composites: memory, frontal (attention and executive function), and global. Follow-up cognitive tests were available in 334 participants after intervention (median, 4.1 years). In multivariate analyses adjusted for confounders, participants allocated to a Mediterranean diet plus olive oil scored better on the RAVLT (P = .049) and Color Trail Test part 2 (P = .04) compared with controls; no between-group differences were observed for the other cognitive tests. Similarly adjusted cognitive composites (mean z scores with 95% CIs) for changes above baseline of the memory composite were 0.04 (-0.09 to 0.18) for the Mediterranean diet plus olive oil, 0.09 (-0.05 to 0.23; P = .04 vs controls) for the Mediterranean diet plus nuts, and -0.17 (-0.32 to -0.01) for the control diet. Respective changes from baseline of the frontal cognition composite were 0.23 (0.03 to 0.43; P = .003 vs controls), 0.03 (-0.25 to 0.31), and -0.33 (-0.57 to -0.09). Changes from baseline of the global cognition composite were 0.05 (-0.11 to 0.21; P = .005 vs controls) for the Mediterranean diet plus olive oil, -0.05 (-0.27 to 0.18) for the Mediterranean diet plus nuts, and -0.38 (-0.57 to -0.18) for the control diet. All cognitive composites significantly (P < .05) decreased from baseline in controls. In an older population, a Mediterranean diet supplemented with olive oil or nuts is associated with improved cognitive function. isrctn.org Identifier: ISRCTN35739639.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 418 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Netherlands 1 <1%
Canada 1 <1%
Brazil 1 <1%
Unknown 414 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 71 17%
Researcher 65 16%
Student > Master 65 16%
Student > Ph. D. Student 48 11%
Other 28 7%
Other 72 17%
Unknown 69 17%
Readers by discipline Count As %
Medicine and Dentistry 117 28%
Nursing and Health Professions 47 11%
Agricultural and Biological Sciences 37 9%
Psychology 34 8%
Neuroscience 28 7%
Other 69 17%
Unknown 86 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 1453. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2020.
All research outputs
#2,869
of 15,574,170 outputs
Outputs from JAMA Internal Medicine
#45
of 4,061 outputs
Outputs of similar age
#33
of 232,616 outputs
Outputs of similar age from JAMA Internal Medicine
#2
of 154 outputs
Altmetric has tracked 15,574,170 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,061 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 135.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 232,616 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.