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Heart Rate Variability Correlates to Functional Aerobic Impairment in Hemodialysis Patients

Overview of attention for article published in Arquivos Brasileiros de Cardiologia, January 2015
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Title
Heart Rate Variability Correlates to Functional Aerobic Impairment in Hemodialysis Patients
Published in
Arquivos Brasileiros de Cardiologia, January 2015
DOI 10.5935/abc.20150039
Pubmed ID
Authors

Maria Angela Magalhães de Queiroz Carreira, André Barros Nogueira, Felipe Montes Pena, Marcio Galindo Kiuchi, Ronaldo Campos Rodrigues, Rodrigo da Rocha Rodrigues, Jorge Paulo Strogoff de Matos, Jocemir Ronaldo Lugon

Abstract

Autonomic dysfunction (AD) is highly prevalent in hemodialysis (HD) patients and has been implicated in their increased risk of cardiovascular mortality. To correlate heart rate variability (HRV) during exercise treadmill test (ETT) with the values obtained when measuring functional aerobic impairment (FAI) in HD patients and controls. Cross-sectional study involving HD patients and a control group. Clinical examination, blood sampling, transthoracic echocardiogram, 24-hour Holter, and ETT were performed. A symptom-limited ramp treadmill protocol with active recovery was employed. Heart rate variability was evaluated in time domain at exercise and recovery periods. Forty-one HD patients and 41 controls concluded the study. HD patients had higher FAI and lower HRV than controls (p<0.001 for both). A correlation was found between exercise HRV (SDNN) and FAI in both groups. This association was independent of age, sex, smoking, body mass index, diabetes, and clonidine or beta-blocker use, but not of hemoglobin levels. No association was found between FAI and HRV on 24-hour Holter or at the recovery period of ETT. Of note, exercise HRV was inversely correlated with FAI in HD patients and controls. (Arq Bras Cardiol. 2015; [online]. ahead print, PP.0-0).

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Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 5%
Unspecified 1 2%
Student > Postgraduate 1 2%
Unknown 37 90%
Readers by discipline Count As %
Unspecified 1 2%
Sports and Recreations 1 2%
Materials Science 1 2%
Neuroscience 1 2%
Unknown 37 90%