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Effects of early life trauma are dependent on genetic predisposition: a rat study

Overview of attention for article published in Behavioral and Brain Functions, May 2011
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Title
Effects of early life trauma are dependent on genetic predisposition: a rat study
Published in
Behavioral and Brain Functions, May 2011
DOI 10.1186/1744-9081-7-11
Pubmed ID
Authors

Toni-Lee Sterley, Fleur M Howells, Vivienne A Russell

Abstract

Trauma experienced early in life increases the risk of developing a number of psychological and/or behavioural disorders. It is unclear, however, how genetic predisposition to a behavioural disorder, such as attention-deficit/hyperactivity disorder (ADHD), modifies the long-term effects of early life trauma. There is substantial evidence from family and twin studies for susceptibility to ADHD being inherited, implying a strong genetic component to the disorder. In the present study we used an inbred animal model of ADHD, the spontaneously hypertensive rat (SHR), to investigate the long-term consequences of early life trauma on emotional behaviour in individuals predisposed to developing ADHD-like behaviour.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 2 2%
United States 2 2%
United Kingdom 1 <1%
Portugal 1 <1%
Spain 1 <1%
Argentina 1 <1%
Unknown 102 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 26%
Researcher 14 13%
Student > Bachelor 14 13%
Student > Postgraduate 11 10%
Student > Master 10 9%
Other 17 15%
Unknown 15 14%
Readers by discipline Count As %
Psychology 26 24%
Agricultural and Biological Sciences 25 23%
Neuroscience 13 12%
Medicine and Dentistry 10 9%
Nursing and Health Professions 3 3%
Other 14 13%
Unknown 19 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2015.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Behavioral and Brain Functions
#316
of 417 outputs
Outputs of similar age
#105,841
of 121,699 outputs
Outputs of similar age from Behavioral and Brain Functions
#5
of 5 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
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