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ISG15 facilitates cellular antiviral response to dengue and west nile virus infection in vitro

Overview of attention for article published in Virology Journal, October 2011
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Title
ISG15 facilitates cellular antiviral response to dengue and west nile virus infection in vitro
Published in
Virology Journal, October 2011
DOI 10.1186/1743-422x-8-468
Pubmed ID
Authors

Jianfeng Dai, Wen Pan, Penghua Wang

Abstract

Dengue virus (DENV) and West Nile virus (WNV), close siblings of the Flaviviridae family, are the causative agents of Dengue hemorraghic shock or West Nile meningoencephalitis respectively. Vaccines against these two flaviviruses are currently unavailable. Interferon- Stimulated Gene 15 (ISG15), encoding an ubiquitin-like protein, is significantly induced by type I interferons or viral infections. Its roles in viral infections, however, vary with viruses, being either anti- or pro-viral. The exact roles of ISG15 in DENV and WNV infections remain unknown. In the current study, we evaluated the relevancies of ISG15 to DENV and WNV infection of a mouse macrophage cell line RAW264.7.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Germany 1 1%
Unknown 72 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 23%
Researcher 11 15%
Student > Master 8 11%
Student > Bachelor 7 9%
Professor 4 5%
Other 14 19%
Unknown 13 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 36%
Immunology and Microbiology 10 14%
Medicine and Dentistry 9 12%
Biochemistry, Genetics and Molecular Biology 8 11%
Veterinary Science and Veterinary Medicine 2 3%
Other 4 5%
Unknown 14 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2011.
All research outputs
#15,236,094
of 22,653,392 outputs
Outputs from Virology Journal
#1,932
of 3,022 outputs
Outputs of similar age
#94,154
of 135,895 outputs
Outputs of similar age from Virology Journal
#43
of 77 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,022 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.