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Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer

Overview of attention for article published in Breast Cancer Research, July 2011
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2 X users

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42 Dimensions

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Title
Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer
Published in
Breast Cancer Research, July 2011
DOI 10.1186/bcr2916
Pubmed ID
Authors

Volkmar Müller, Sabine Riethdorf, Brigitte Rack, Wolfgang Janni, Peter A Fasching, Erich Solomayer, Bahriye Aktas, Sabine Kasimir-Bauer, Julia Zeitz, Klaus Pantel, Tanja Fehm, the DETECT study group

Abstract

Circulating tumor cells (CTCs) reflect aggressive tumor behavior by hematogenous tumor cell dissemination. The tissue inhibitor of metalloproteinase 1 (TIMP-1) plays a role in tissue invasion and is also involved in angiogenesis, abrogation of apoptosis and in chemoresistance. Carbonic anhydrase IX (CAIX) is a metalloenzyme involved in cell adhesion, growth and survival of tumor cells. The aim of the study was to investigate whether serum concentrations of TIMP-1 and CAIX are associated with the detection of CTC in metastatic breast cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Unknown 49 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 24%
Researcher 10 20%
Student > Master 8 16%
Student > Doctoral Student 4 8%
Student > Bachelor 4 8%
Other 4 8%
Unknown 8 16%
Readers by discipline Count As %
Medicine and Dentistry 19 38%
Agricultural and Biological Sciences 10 20%
Biochemistry, Genetics and Molecular Biology 4 8%
Chemistry 3 6%
Nursing and Health Professions 2 4%
Other 1 2%
Unknown 11 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2011.
All research outputs
#15,169,543
of 25,374,647 outputs
Outputs from Breast Cancer Research
#1,328
of 2,053 outputs
Outputs of similar age
#86,068
of 128,029 outputs
Outputs of similar age from Breast Cancer Research
#11
of 19 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 128,029 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.