Title |
Perfluorinated compounds are related to breast cancer risk in greenlandic inuit: A case control study
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Published in |
Environmental Health, October 2011
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DOI | 10.1186/1476-069x-10-88 |
Pubmed ID | |
Authors |
Eva C Bonefeld-Jorgensen, Manhai Long, Rossana Bossi, Pierre Ayotte, Gert Asmund, Tanja Krüger, Mandana Ghisari, Gert Mulvad, Peder Kern, Peter Nzulumiki, Eric Dewailly |
Abstract |
Breast cancer (BC) is the most common cancer for women in the western world. From very few cases an extraordinary increase in BC was observed in the Inuit population of Greenland and Canada although still lower than in western populations. Previous data suggest that exposure to persistent organic pollutants (POPs) might contribute to the risk of BC. Rat studies showed that perfluorinated compounds (PFCs) cause significantly increase in mammary fibroadenomas. This study aimed at evaluating the association between serum levels of POPs/PFCs in Greenlandic Inuit BC cases and their controls, and whether the combined POP related effect on nuclear hormone receptors affect BC risk. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 33% |
Canada | 2 | 22% |
United Kingdom | 1 | 11% |
Germany | 1 | 11% |
Unknown | 2 | 22% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | <1% |
Norway | 1 | <1% |
Mexico | 1 | <1% |
Nigeria | 1 | <1% |
United States | 1 | <1% |
Unknown | 175 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 36 | 20% |
Student > Master | 24 | 13% |
Researcher | 21 | 12% |
Student > Bachelor | 16 | 9% |
Student > Doctoral Student | 9 | 5% |
Other | 29 | 16% |
Unknown | 45 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Environmental Science | 37 | 21% |
Medicine and Dentistry | 28 | 16% |
Chemistry | 12 | 7% |
Agricultural and Biological Sciences | 10 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 6% |
Other | 38 | 21% |
Unknown | 45 | 25% |