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Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability

Overview of attention for article published in Neuroscience & Biobehavioral Reviews, August 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

news
1 news outlet
twitter
3 tweeters

Citations

dimensions_citation
23 Dimensions

Readers on

mendeley
30 Mendeley
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Title
Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability
Published in
Neuroscience & Biobehavioral Reviews, August 2015
DOI 10.1016/j.neubiorev.2015.05.010
Pubmed ID
Authors

Vladan Bajic, Biljana Spremo-Potparevic, Lada Zivkovic, Esma R. Isenovic, Thomas Arendt

Abstract

Neurons are postmitotic cells that are in permanent cell cycle arrest. However, components of the cell cycle machinery that are expressed in Alzheimer 's disease (AD) neurons are showing features of a cycling cell and those attributed to a postmitotic cell as well. Furthermore, the unique physiological operations taking place in neurons, ascribed to "core cell cycle regulators" are also key regulators in cell division. Functions of these cell cycle regulators include neuronal migration, axonal elongation, axon pruning, dendrite morphogenesis and synaptic maturation and plasticity. In this review, we focus on cohesion and cohesion related proteins in reference to their neuronal functions and how impaired centromere/cohesion dynamics may connect cell cycle dysfunction to aneuploidy in AD.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 29 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 20%
Professor 4 13%
Student > Postgraduate 3 10%
Student > Master 3 10%
Student > Bachelor 2 7%
Other 6 20%
Unknown 6 20%
Readers by discipline Count As %
Medicine and Dentistry 6 20%
Agricultural and Biological Sciences 5 17%
Neuroscience 3 10%
Psychology 3 10%
Biochemistry, Genetics and Molecular Biology 2 7%
Other 4 13%
Unknown 7 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2016.
All research outputs
#1,215,304
of 12,294,798 outputs
Outputs from Neuroscience & Biobehavioral Reviews
#507
of 2,232 outputs
Outputs of similar age
#31,461
of 235,033 outputs
Outputs of similar age from Neuroscience & Biobehavioral Reviews
#9
of 43 outputs
Altmetric has tracked 12,294,798 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,232 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,033 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.