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Gout and the risk of dementia: a nationwide population-based cohort study

Overview of attention for article published in Arthritis Research & Therapy, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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3 news outlets
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81 Dimensions

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Title
Gout and the risk of dementia: a nationwide population-based cohort study
Published in
Arthritis Research & Therapy, May 2015
DOI 10.1186/s13075-015-0642-1
Pubmed ID
Authors

Jen-Yee Hong, Tzuo-Yun Lan, Gau-Jun Tang, Chao-Hsiun Tang, Tzeng-Ji Chen, Hsiao-Yi Lin

Abstract

Uric acid was proposed to have anti-oxidant property and possible neuroprotective effects. We examined the association between gout and dementia with population database. The study utilized the claims data from the nationwide representative sample of Taiwan National Health Insurance Research Database (NHIRD). We ascertained patients with gout and dementia covering vascular and non-vascular (including Alzheimer's) subtypes using International Classification of Diseases Ninth Revision, Clinical Modification (ICD9-CM) codes. A control group matched on sex, age, and index date of gout patients was randomly sampled with a ratio of 1:4 from the same database for comparison. From 2002 to 2008, 28,769 gout patients who were older than 50 years old were identified, and 114,742 control patients was matched into the study. During follow-up, 7,119 patients developed dementia (1,214 with gout, and 5,905 without gout). After adjusting for age, sex, and relevant comorbidities, a Cox regression analysis showed that gout patients had a lower risk of developing non-vascular dementia (hazard ratio (HR): 0.77; 95% confidence interval (CI): 0.72 - 0.83; p < 0.001) and vascular dementia (HR: 0.76; 95% CI: 0.65 - 0.88; p < 0.001). Patients with gout have a lower risk of developing dementia. This phenomenon exists for both non-vascular and vascular types of dementia.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
United States 1 3%
Unknown 33 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 17%
Student > Master 5 14%
Student > Bachelor 4 11%
Student > Ph. D. Student 3 9%
Other 2 6%
Other 7 20%
Unknown 8 23%
Readers by discipline Count As %
Medicine and Dentistry 14 40%
Mathematics 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Psychology 2 6%
Agricultural and Biological Sciences 1 3%
Other 4 11%
Unknown 10 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2022.
All research outputs
#1,703,596
of 25,371,288 outputs
Outputs from Arthritis Research & Therapy
#240
of 3,381 outputs
Outputs of similar age
#21,167
of 280,030 outputs
Outputs of similar age from Arthritis Research & Therapy
#7
of 62 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,030 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.