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Enhanced pupillary light reflex in infancy is associated with autism diagnosis in toddlerhood

Overview of attention for article published in Nature Communications, May 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

news
10 news outlets
blogs
2 blogs
twitter
25 X users
facebook
7 Facebook pages

Citations

dimensions_citation
73 Dimensions

Readers on

mendeley
144 Mendeley
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Title
Enhanced pupillary light reflex in infancy is associated with autism diagnosis in toddlerhood
Published in
Nature Communications, May 2018
DOI 10.1038/s41467-018-03985-4
Pubmed ID
Authors

Pär Nyström, Teodora Gliga, Elisabeth Nilsson Jobs, Gustaf Gredebäck, Tony Charman, Mark H. Johnson, Sven Bölte, Terje Falck-Ytter

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting around 1% of the population. We previously discovered that infant siblings of children with ASD had stronger pupillary light reflexes compared to low-risk infants, a result which contrasts sharply with the weak pupillary light reflex typically seen in both children and adults with ASD. Here, we show that on average the relative constriction of the pupillary light reflex is larger in 9-10-month-old high risk infant siblings who receive an ASD diagnosis at 36 months, compared both to those who do not and to low-risk controls. We also found that the magnitude of the pupillary light reflex in infancy is associated with symptom severity at follow-up. This study indicates an important role of sensory atypicalities in the etiology of ASD, and suggests that pupillometry, if further developed and refined, could facilitate risk assessment in infants.

X Demographics

X Demographics

The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 144 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 144 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 14%
Researcher 19 13%
Student > Master 19 13%
Other 12 8%
Student > Doctoral Student 12 8%
Other 27 19%
Unknown 35 24%
Readers by discipline Count As %
Psychology 40 28%
Neuroscience 24 17%
Medicine and Dentistry 14 10%
Engineering 6 4%
Design 3 2%
Other 11 8%
Unknown 46 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 94. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2019.
All research outputs
#431,297
of 24,652,720 outputs
Outputs from Nature Communications
#7,229
of 53,344 outputs
Outputs of similar age
#9,923
of 333,149 outputs
Outputs of similar age from Nature Communications
#178
of 1,158 outputs
Altmetric has tracked 24,652,720 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 53,344 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 56.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,149 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 1,158 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.