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Clinical and laboratory features of urinary tract infections in young infants

Overview of attention for article published in Jornal Brasileiro de Nefrologia, March 2018
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Title
Clinical and laboratory features of urinary tract infections in young infants
Published in
Jornal Brasileiro de Nefrologia, March 2018
DOI 10.1590/1678-4685-jbn-3602
Pubmed ID
Authors

Denise Swei Lo, Larissa Rodrigues, Vera Hermina Kalika Koch, Alfredo Elias Gilio

Abstract

Urinary tract infection (UTI) is the most common serious bacterial infection in young infants. Signs and symptoms are often nonspecific. To describe clinical, demographic and laboratory features of UTI in infants ≤ 3 months old. Cross-sectional study of infants ≤ 3 months old with UTI diagnosed in a pediatric emergency department, for the period 2010-2012. UTI was defined as ≥ 50,000 colony-forming units per milliliter of a single uropathogen isolated from bladder catheterization. Paired urinalysis and urine culture from group culture-positive and group culture-negative were used to determine the sensitivity and specificity of pyuria and nitrite tests in detecting UTI. Of 519 urine cultures collected, UTI was diagnosed in 65 cases (prevalence: 12.5%); with male predominance (77%). The most common etiologies were Escherichia coli (56.9%), Klebsiella pneumoniae (18.5%) and Enterococcus faecalis (7.7%). Frequent clinical manifestations were fever (77.8%), irritability (41.4%) and vomiting (25.4%). The median temperature was 38.7°C. The sensitivity of the nitrite test was 30.8% (95%CI:19.9-43.4%), specificity of 100% (95%CI:99.2-100%). Pyuria ≥ 10,000/mL had a sensitivity of 87.7% (95%CI:77.2-94.5%), specificity of 74.9% (95%CI:70.6 -78.8%). The median peripheral white blood cell count was 13,150/mm3; C-reactive protein levels were normal in 30.5% of cases. The male: female ratio for urinary tract infection was 3.3:1. Non-Escherichia coli etiologies should be considered in empirical treatment. Fever was the main symptom. Positive nitrite is highly suggestive of UTI but has low sensitivity; whereas pyuria ≥ 10,000/mL revealed good sensitivity, but low specificity. Peripheral white blood cell count and C-reactive protein concentration have limited usefulness to suggest UTI.

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Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 14%
Student > Master 7 11%
Researcher 7 11%
Student > Postgraduate 6 9%
Student > Doctoral Student 4 6%
Other 13 20%
Unknown 19 29%
Readers by discipline Count As %
Medicine and Dentistry 26 40%
Agricultural and Biological Sciences 4 6%
Nursing and Health Professions 3 5%
Immunology and Microbiology 3 5%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 8 12%
Unknown 19 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2022.
All research outputs
#14,577,528
of 21,699,130 outputs
Outputs from Jornal Brasileiro de Nefrologia
#132
of 292 outputs
Outputs of similar age
#186,777
of 297,754 outputs
Outputs of similar age from Jornal Brasileiro de Nefrologia
#1
of 2 outputs
Altmetric has tracked 21,699,130 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 292 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,754 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them