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Chlorhexidine for prevention of alveolar osteitis: a randomised clinical trial

Overview of attention for article published in Journal of Applied Oral Science, May 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (62nd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

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136 Mendeley
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Title
Chlorhexidine for prevention of alveolar osteitis: a randomised clinical trial
Published in
Journal of Applied Oral Science, May 2018
DOI 10.1590/1678-7757-2017-0245
Pubmed ID
Authors

Diego Halabi, Jose Escobar, Cyntia Alvarado, Nicolette Martinez, Carlos Muñoz

Abstract

Objective To determine the effectiveness of chlorhexidine 0.12% mouthwash (CHX) after tooth extraction for the prevention of alveolar osteitis (AO). Material and methods We conducted a double-blind randomised clinical trial stratified by risk factors. We enrolled a cohort of 822 patients who underwent dental extractions, and were considered to be at risk of developing AO (previous surgical site infection, traumatic extraction, and tobacco smoking). After extraction, patients were randomly allocated for CHX group or placebo group, matched by risk factors. The primary outcome was clinical diagnosis of AO: increasing postoperative pain for 4 d within and around the socket, and total or partial breakdown of the blood clot in the socket with or without bone exposure. Results Follow-up was completed by 744 participants (372 chlorhexidine and 372 placebo). We detected no significant differences between the two groups at baseline. After completed follow-up, risk factors were equally distributed between the two groups. Overall incidence of OA was 4.97%, in which 27 participants treated with placebo (7.26%) and 10 participants treated with CHX (2.69%) developed AO. CHX reduced the incidence of AO by 63% [Absolute Risk Reduction: 4.57 (95% CI 1.5-7.7), Number Needed to Treat: 21.88 (95% CI 13.0-69.3), Fisher's exact test: p=0.006]. No adverse effects were reported. Conclusion The use of chlorhexidine 0.12% mouthwash after tooth extraction is safe and effective in reducing the incidence of AO in high-risk patients.

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X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 136 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 24 18%
Student > Postgraduate 11 8%
Student > Master 10 7%
Other 7 5%
Lecturer 6 4%
Other 19 14%
Unknown 59 43%
Readers by discipline Count As %
Medicine and Dentistry 56 41%
Biochemistry, Genetics and Molecular Biology 4 3%
Social Sciences 3 2%
Nursing and Health Professions 3 2%
Arts and Humanities 2 1%
Other 7 5%
Unknown 61 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2022.
All research outputs
#8,299,243
of 26,430,863 outputs
Outputs from Journal of Applied Oral Science
#84
of 625 outputs
Outputs of similar age
#129,563
of 345,610 outputs
Outputs of similar age from Journal of Applied Oral Science
#2
of 10 outputs
Altmetric has tracked 26,430,863 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 625 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,610 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.