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Attention Score in Context
| Title |
Numerical study of entrainment of the human circadian system and recovery by light treatment
|
|---|---|
| Published in |
Theoretical Biology and Medical Modelling, May 2018
|
| DOI | 10.1186/s12976-018-0077-x |
| Pubmed ID | |
| Authors |
Soon Ho Kim, Segun Goh, Kyungreem Han, Jong Won Kim, MooYoung Choi |
| Abstract |
While the effects of light as a zeitgeber are well known, the way the effects are modulated by features of the sleep-wake system still remains to be studied in detail. A mathematical model for disturbance and recovery of the human circadian system is presented. The model combines a circadian oscillator and a sleep-wake switch that includes the effects of orexin. By means of simulations, we characterize the period-locking zone of the model, where a stable 24-hour circadian rhythm exists, and the occurrence of circadian disruption due to both insufficient light and imbalance in orexin. We also investigate how daily bright light treatments of short duration can recover the normal circadian rhythm. It is found that the system exhibits continuous phase advance/delay at lower/higher orexin levels. Bright light treatment simulations disclose two optimal time windows, corresponding to morning and evening light treatments. Among the two, the morning light treatment is found effective in a wider range of parameter values, with shorter recovery time. This approach offers a systematic way to determine the conditions under which circadian disruption occurs, and to evaluate the effects of light treatment. In particular, it could potentially offer a way to optimize light treatments for patients with circadian disruption, e.g., sleep and mood disorders, in clinical settings. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 27% |
| Student > Bachelor | 3 | 14% |
| Researcher | 2 | 9% |
| Student > Doctoral Student | 1 | 5% |
| Professor | 1 | 5% |
| Other | 5 | 23% |
| Unknown | 4 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 4 | 18% |
| Nursing and Health Professions | 2 | 9% |
| Physics and Astronomy | 2 | 9% |
| Unspecified | 1 | 5% |
| Mathematics | 1 | 5% |
| Other | 4 | 18% |
| Unknown | 8 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2018.
All research outputs
#20,486,884
of 23,049,027 outputs
Outputs from Theoretical Biology and Medical Modelling
#246
of 287 outputs
Outputs of similar age
#288,130
of 327,423 outputs
Outputs of similar age from Theoretical Biology and Medical Modelling
#2
of 3 outputs
Altmetric has tracked 23,049,027 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 287 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,423 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.