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X Demographics
Mendeley readers
Attention Score in Context
| Title |
High prevalence of HIV-1 transmitted drug resistance among therapy-naïve Burmese entering travelers at Dehong ports in Yunnan, China
|
|---|---|
| Published in |
BMC Infectious Diseases, May 2018
|
| DOI | 10.1186/s12879-018-3130-9 |
| Pubmed ID | |
| Authors |
Qicai Xuan, Shuwen Liang, Weihong Qin, Shuting Yang, A-mei Zhang, Ting Zhao, Hui Su, Zhiqing Xia, Binghui Wang, Xueshan Xia |
| Abstract |
The overall success of Human immunodeficiency virus type 1 (HIV-1) antiretroviral therapy (ART) was heavily challenged upon the occurrence of drug resistance. Dehong Prefecture witnessed not only the first report of HIV-1 infection but also the experimental adoption of antiviral treatment in China. The transmission and epidemic of HIV-1 in Dehong is impacted by cross-border activities. The characteristics of HIV-1 drug resistance among therapy-naïve Burmese entering travelers in Yunnan and their speculated origin are still not clarified. Two hundred ninety-eight HIV-1 infected Burmese entering travelers at Dehong ports were recruited between 2003 and 2012. The partial HIV-1 pol gene fragments were amplified and sequenced for the analysis of drug-resistance mutations (DRMs). Phylogenetic analysis on gag-pol gene was conducted to elucidate phylogenetic and evolutionary characteristics of these drug resistant strains. It was figured out that the occurrence ratio of HIV-1 drug resistance among HIV-1 infected entering travelers from Myanmar was up to 12.8%. The resistant mutations covered several types, including one type of PI mutations (L33F), six types of NRTI mutations and seven types of NNRTI. Close genetic relationship was observed in the phylogenetic analysis on gag-pol gene among the drug resistant strains respectively from Dehong, other Yunnan areas, neighboring provinces (Guangxi) and neighboring countries (Thailand and Myanmar). The findings in this study revealed that HIV drug resistant locus is spreading from the population who is receiving drug-resistance treatment to the new infectors, which indicates the urgency of surveillance work on drug resistance among the migrant population with high risks of HIV infection. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Venezuela, Bolivarian Republic of | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 43 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 21% |
| Student > Master | 6 | 14% |
| Student > Ph. D. Student | 4 | 9% |
| Other | 2 | 5% |
| Student > Doctoral Student | 2 | 5% |
| Other | 0 | 0% |
| Unknown | 20 | 47% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 12% |
| Nursing and Health Professions | 4 | 9% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Environmental Science | 1 | 2% |
| Agricultural and Biological Sciences | 1 | 2% |
| Other | 6 | 14% |
| Unknown | 23 | 53% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2018.
All research outputs
#18,612,022
of 23,055,429 outputs
Outputs from BMC Infectious Diseases
#5,662
of 7,733 outputs
Outputs of similar age
#253,922
of 327,697 outputs
Outputs of similar age from BMC Infectious Diseases
#95
of 138 outputs
Altmetric has tracked 23,055,429 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,733 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,697 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.