Title |
Vitamin D and juvenile idiopathic arthritis
|
---|---|
Published in |
Pediatric Rheumatology, May 2018
|
DOI | 10.1186/s12969-018-0250-0 |
Pubmed ID | |
Authors |
Sarah L. Finch, Alan M. Rosenberg, Hassan Vatanparast |
Abstract |
Vitamin D has been implicated in the pathogenesis of autoimmune diseases. While the roles of vitamin D in other autoimmune diseases have been investigated, less is known about the role of vitamin D in chronic childhood arthritis. This review summarizes and evaluates evidence relating to 25-hydroxyvitamin D (25(OH)D) and chronic childhood arthritis. A scoping literature review was conducted using Ovid Medline, Ovid Embase, Cumulative Index to Nursing and Allied Health Literature, Web of Science and Scopus. Further, we geo-mapped the results of the studies to identify the patterns of the association between vitamin D and chronic childhood arthritis across the globe. Of 38 studies reporting 25(OH)D concentrations in childhood chronic arthritis, 32 (84.2%) reported that a significant number of children had suboptimal (< 75 nmol/L) status. The data indicate suboptimal vitamin D status in children with chronic arthritis. Further, the association between low vitamin D and increased arthritis activity follow a north-south geographical gradient. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 3 | 27% |
El Salvador | 1 | 9% |
Unknown | 7 | 64% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 73% |
Practitioners (doctors, other healthcare professionals) | 2 | 18% |
Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 65 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 17% |
Student > Bachelor | 8 | 12% |
Other | 5 | 8% |
Student > Postgraduate | 5 | 8% |
Professor | 4 | 6% |
Other | 14 | 22% |
Unknown | 18 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 42% |
Nursing and Health Professions | 8 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Unspecified | 2 | 3% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Other | 4 | 6% |
Unknown | 19 | 29% |