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Early dynamic left intraventricular obstruction is associated with hypovolemia and high mortality in septic shock patients

Overview of attention for article published in Critical Care, June 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

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39 tweeters
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1 Facebook page

Citations

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31 Dimensions

Readers on

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63 Mendeley
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Title
Early dynamic left intraventricular obstruction is associated with hypovolemia and high mortality in septic shock patients
Published in
Critical Care, June 2015
DOI 10.1186/s13054-015-0980-z
Pubmed ID
Authors

Jean-Louis Chauvet, Shari El-Dash, Olivier Delastre, Bernard Bouffandeau, Dominique Jusserand, Jean-Baptiste Michot, Fabrice Bauer, Julien Maizel, Michel Slama

Abstract

Based on previously published case reports demonstrating dynamic left intraventricular obstruction (IVO) triggered by hypovolemia or catecholamines, this study aimed to establish: (1) its occurrence in septic-shock patients; (2) correlation between this intraventricular gradient (IVG) with volume status and fluid responsiveness; (3) mortality rate. We prospectively analyzed patients with septic shock admitted to a general ICU over a 28 month period who presented Doppler signs of IVO. Clinical characteristics and hemodynamic parameters as well as echocardiographic data regarding left ventricular function, size, and calculated mass, as well as left-ventricular outflow Doppler pattern and velocity before and after fluid infusions were recorded. 218 patients with septic shock were admitted in our ICU during the study period. IVO was observed in 47 (22 %) patients. Mortality rate at 28 days was found to be higher in patients with than in patients without IVO (55 % vs 33 % p < 0.01). Small, hypercontractile left ventricles, (end-diastolic LV surface 4.7 ± 2.1 cm(2)/m(2) and ejection fraction 82 ± 12 %), and frequently pseudohypertrophic were found in these patients. A rise of ≥ 12 % in stroke index was found in 87 % patients with IVO with drop of 47 % of intra ventricular obstruction after fluid infusion. Left intraventricular obstruction is a frequent event in septic shock patients bearing an important correlation with fluid-responsiveness. Mortality rate was found to be higher in these patients in comparison with patients without obstruction.

Twitter Demographics

The data shown below were collected from the profiles of 39 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 10 16%
Researcher 9 14%
Professor > Associate Professor 8 13%
Other 8 13%
Student > Doctoral Student 4 6%
Other 15 24%
Unknown 9 14%
Readers by discipline Count As %
Medicine and Dentistry 48 76%
Nursing and Health Professions 1 2%
Social Sciences 1 2%
Arts and Humanities 1 2%
Unknown 12 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2020.
All research outputs
#889,777
of 15,912,337 outputs
Outputs from Critical Care
#851
of 5,027 outputs
Outputs of similar age
#15,796
of 235,732 outputs
Outputs of similar age from Critical Care
#1
of 4 outputs
Altmetric has tracked 15,912,337 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,027 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,732 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them